Choline-d9 chloride
Based on 3 publication(s) in Google Scholar
Choline-d9 chloride is the d9-labeled Choline chloride (HY-B1337). Choline chloride is an orally active methylxanthine derivative. Choline chloride exhibits weak antihistaminic and anticholinergic activities and potentiates the effects of histamine and acetylcholine. Choline chloride relaxes bronchial smooth muscle, dilates coronary and peripheral blood vessels, increases urine output and electrolyte excretion, stimulates locomotor activity in the central nervous system, and induces transient hypotension following a pressor phase. Choline chloride modulates sleep architecture by increasing wakefulness time and reducing slow-wave sleep, without altering the frequency or severity of nocturnal hypoxemia, apnea, or hypopnea events. Choline chloride is used in studies of bronchospasm, nocturnal asthma, and chronic asthma.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.98%
- CAS 番号: 61037-86-3
- 分子式: C5H5D9ClNO
- 分子量:148.68
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保管条件:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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生物活性
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化学情報
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溶剤 & 溶解度
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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MedChemExpress（MCE）の使用を引用している文献 Choline-d9 chloride
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生物活性
製品説明
IC50 & Target
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Human Endogenous Metabolite |
臨床実験
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | 2011-05 | PHASE1 |
アプリケーション
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 61037-86-3
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非標識Cas 67-48-1
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性状 Solid
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分子量 148.68
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分子式 C5H5D9ClNO
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Color Off-white to light yellow
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SMILES
[2H]C([2H])([2H])[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])CCO.[Cl-]
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別名
コリンクロリド-(トリメチル-d9); 塩化コリン-d9
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (3)
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Journal Impact Factor
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Most Recent
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Anal Chem
In Situ Derivatization Combined with DESI-MRM-MS/MS for Spatial Mapping Intratissue Amine-Containing Metabolites, Trimethylamine as a Case. [Abstract]2026 Feb 7. PMID: 41653191 -
Clin Chim Acta
SAH and SAM/SAH ratio associate with acute kidney injury in critically ill patients: A case-control study. [Abstract]2024 Jan 15:553:117726. PMID: 38110027 -
J Chromatogr B Analyt Technol Biomed Life Sci
Simultaneous determination of choline, L-carnitine, betaine, trimethylamine, trimethylamine N-oxide, and creatinine in plasma, liver, and feces of hyperlipidemic rats by UHPLC-MS/MS. [Abstract]2024 Aug 1:1243:124210. PMID: 38936270
溶剤 & 溶解度
体外:
DMSO : ≥ 140 mg/mL (941.62 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : ≥ 100 mg/mL (672.59 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (279 KB)
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SDS (394 KB)
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- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 6.7259 mL | 33.6293 mL | 67.2585 mL | 168.1464 mL |
| 5 mM | 1.3452 mL | 6.7259 mL | 13.4517 mL | 33.6293 mL | |
| 10 mM | 0.6726 mL | 3.3629 mL | 6.7259 mL | 16.8146 mL | |
| 15 mM | 0.4484 mL | 2.2420 mL | 4.4839 mL | 11.2098 mL | |
| 20 mM | 0.3363 mL | 1.6815 mL | 3.3629 mL | 8.4073 mL | |
| 25 mM | 0.2690 mL | 1.3452 mL | 2.6903 mL | 6.7259 mL | |
| 30 mM | 0.2242 mL | 1.1210 mL | 2.2420 mL | 5.6049 mL | |
| 40 mM | 0.1681 mL | 0.8407 mL | 1.6815 mL | 4.2037 mL | |
| 50 mM | 0.1345 mL | 0.6726 mL | 1.3452 mL | 3.3629 mL | |
| 60 mM | 0.1121 mL | 0.5605 mL | 1.1210 mL | 2.8024 mL | |
| 80 mM | 0.0841 mL | 0.4204 mL | 0.8407 mL | 2.1018 mL | |
| 100 mM | 0.0673 mL | 0.3363 mL | 0.6726 mL | 1.6815 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Choline-d9 chloride 関連分類
HY-B1337S1 関連分類
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