2. Signaling Pathways
  3. GPCR/G Protein
    Immunology/Inflammation
    Neuronal Signaling
  4. Histamine Receptor
  5. H4 Receptor Isoform

H4 Receptor

 

H4 Receptor Related Products (16):

Cat. No. Product Name Effect Purity
  • HY-B0527A
    Amitriptyline hydrochloride
    		Inhibitor 99.56%
    Amitriptyline hydrochloride is an inhibitor of serotonin reuptake transporter (SERT) and noradrenaline reuptake transporter (NET), with Kis of 3.45 nM and 13.3 nM for human SERT and NET, respectively.
  • HY-13508
    JNJ-7777120
    		Antagonist 99.97%
    JNJ-7777120 is a potent and selective histamine H4 receptor antagonist (Ki=4.5 nM).
  • HY-101189
    JNJ-39758979
    		Antagonist ≥98.0%
    JNJ-39758979 is a selective, orally active, and high-affinity histamine H4 receptor antagonist with Kis of 12.5, 5.3, and 25 nM for human, mouse, and monkey histamine H4 receptor, respectively.
  • HY-16756
    Toreforant
    		Antagonist 99.82%
    Toreforant is a potent and selective histamine H4 receptor (H4R) antagonist, with a Ki at the human receptor of 8.4 nM.
  • HY-107560
    4-Methylhistamine dihydrochloride
    		Agonist ≥99.0%
    4-Methylhistamine (dihydrochloride) is the potent agonist of histamine 4 receptor (H4R).
  • HY-120541
    ST-1006
    		Agonist
    ST-1006 is a potent histamine H4 receptor agonist with a pKi value of 7.94.
  • HY-107558
    JNJ10191584 maleate
    		Antagonist
    JNJ10191584 (VUF6002) maleate (compound 40) is an orally active and selective histamine H4 receptor antagonist with a Ki value of 26 nM.
  • HY-113936
    A-943931
    		Antagonist
    A-943931 is a potent and selective histamine H4 receptor (H4R) antagonist with pKi values of 4.6, 3.8 nM for human and rat H4R, respectively.
  • HY-101198
    Clobenpropit dihydrobromide
    		Modulator
    Clobenpropit dihydrobromide is a potent histamine H3R antagonist/inverse agonist with a pEC50 of 8.07 for histamine H3LR.
  • HY-111501
    H4R antagonist 1
    		Antagonist 98.37%
    H4R antagonist 1 is a potent and highly selective histamine H4 receptor (H4R) antagonist with an IC50 of 27 nM.
  • HY-101188
    INCB38579
    		Antagonist 99.97%
    INCB38579 is an orally active, highly brain penetrable, and selective histamine H4 receptor (HH4R) antagonist (hH4R IC50=4.8 nM, mH4R IC50=42 nM, rH4R IC50=32 nM).
  • HY-101173
    Imetit dihydrobromide
    		Agonist
    Imetit dihydrobromide (VUF 8325 dihydrobromide) is a high affinity and potent agonist of histamine H3 and H4 receptors, with Ki values of 0.3 and 2.7 nM, respectively.
  • HY-101189B
    JNJ-39758979 dihydrochloride
    		Antagonist
    JNJ-39758979 dihydrochloride is a selective, orally active, and high-affinity histamine H4 receptor antagonist, with Kis of 12.5, 5.3, and 25 nM for human, mouse, and monkey histamine H4 receptor, respectively.
  • HY-114025
    H4 Receptor antagonist 1
    		Inhibitor 99.66%
    H4 Receptor antagonist 1 is a potent and selective histamine H4 receptor inverse agonist, with an IC50 of 19 nM.
  • HY-147276
    Izuforant
    		Antagonist
    Izuforant (JW1601) (Compound 24) is an orally active histamine H4 receptor (H4R) antagonist with an IC50 of 36 nM against human H4R.
  • HY-123532
    JNJ10191584
    		Antagonist
    JNJ10191584 (VUF6002) is an orally active and selective histamine H4 receptor antagonist with a Ki value of 26 nM.