1196994-11-2
1196994-11-2
Chemical Structure
ST-1006
- CAS No.: 1196994-11-2
- Formula:C16H20Cl2N6
- Molecular Weight:367.28
IUPAC Name: N4-(2,6-dichlorobenzyl)-6-(4-methylpiperazin-1-yl)pyrimidine-2,4-diamine
InChIKey: ICAQZJCLBRKWBG-UHFFFAOYSA-N
SMILES: ClC(C=CC=C1Cl)=C1CNC2=CC(N3CCN(CC3)C)=NC(N)=N2
Biological Activity: ST-1006 is a potent histamine H4 receptor agonist with a pKi value of 7.94. ST-1006 has anti-inflammatory effect[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ST-1006 | 99.55% | ST-1006 is a potent histamine H4 receptor agonist with a pKi value of 7.94. ST-1006 has anti-inflammatory effect. | ||||||||||||||||||||
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References
- [1]. Adami M, et, al. Differential effects of functionally different histamine H4 receptor ligands on acute irritant dermatitis in mice. Naunyn Schmiedebergs Arch Pharmacol. 2018 Dec;391(12):1387-1397. [Content Brief]
- [2]. Mommert S, et, al. Human basophil chemotaxis and activation are regulated via the histamine H4 receptor. Allergy. 2016 Sep;71(9):1264-73. [Content Brief]
Keywords
