2. Recombinant Proteins
  3. CD Antigens
  4. Macrophage CD Proteins Monocyte CD Proteins
  5. LIGHT/CD258

LIGHT/CD258

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Cat. No. Product Name / Synonyms Species Source
  • HY-P73837A
    LIGHT/TNFSF14 Protein, Mouse (sf9, His, solution)

    Tumor necrosis factor ligand superfamily member 14; TNFSF14; HVEM-L; LIGHT  

    		Mouse Sf9 insect cells
    LIGHT/TNFSF14 protein (CD258; TNFRSF14) is a type II transmembrane protein produced by activated T cells. It is a TNFRSF14/HVEM ligand and belongs to the tumor necrosis factor (TNF) family. LIGHT/TNFSF14 is mainly expressed in spleen, with two subtypes: membrane-bound type and soluble type . LIGHT/TNFSF14 protein can be used as immune checkpoint molecule of tumor, and stimulate natural killer cells to produce interferon TFNγ, triggering tumor apoptosis signal . LIGHT/TNFSF14 is also involved in the dominant LTβR-NIK-p52 NF-κB pathway promoting the expression of inflammatory gene. In addition, LIGHT/TNFSF14 protein is a co-stimulatory factor that activates lymphoid cells and has an inhibitory effect on herpes virus infection. Mouse LIGHT/TNFSF14 Protein has 239 amino acids and a transmembrane domain (38-58 a.a.). LIGHT/TNFSF14 Protein, Mouse (sf9, His, solution) is the extracellular part (D72-V239) of mouse LIGHT/TNFSF14 Protein in solution form, produced by Sf9 insect cells, with N-terminal His-tag.
Cat. No. Product Name Effect Purity