1. Screening Libraries
  2. Exosomes Compound Library

Exosomes Compound Library

Cat. No.: HY-L072
Library Contents: XLSX PDF SDF

Exosomes are small membrane vesicles of endocytic origin that are secreted by most cells in culture. Exosomes contain nucleic acids, proteins, lipids, amino acids, and metabolites, etc. Their diverse constituents can reflect their cell of origin. Exosomes are associated with immune responses, viral pathogenicity, pregnancy, cardiovascular diseases, central nervous system-related diseases, and cancer progression. Proteins, metabolites, and nucleic acids delivered by exosomes into recipient cells effectively alter their biological response. Such exosome-mediated responses can be disease promoting or restraining.

The biology of exosomes in disease is still emerging, and the number of studies addressing their utility in the diagnosis and treatment of various pathologies has increased substantially. MCE supplies a unique collection of 36 compounds with the activity of inhibiting or stimulating exsomes secretion/biosynthesis. MCE Exosomes Compound Library is a useful tool for exsomes research.

MCE Exosomes Compound Library can be supplied as pre-dissolved Solutions or Solid. For pre-dissolved solutions in this library, there are 33 compounds supplied in 10 mM solution, 1 compounds supplied in 2 mM solution and 2 compounds supplied in 3 mg/mL solution.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

  • 96-well Plate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
Size (Pre-dissolved Solution or Solid) Price Stock
100 μL/well Solution (10 mM) Get quote In-stock
2 × 100 μL/well Solution (10 mM) Get quote In-stock

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Description
& Advantages

•   A unique collection of 36 exsomes secretion-related small molecules.

•   A useful tool for drug discovery of exsomes secretion-related diseases.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some inhibitors have been approved by FDA.

•   Structurally diverse, medicinally active, and cell permeable.

•   More detailed compound information with structure, IC50, and brief introduction.

•   NMR and HPLC validated to ensure high purity and quality.

•   All compounds are in stock and continuously updated.

Product Details
Formulation:
A collection of 36 exosomes compounds supplied as pre-dissolved Solutions or Solid
Solution: 33 compounds supplied in 10 mM solution, 1 compounds supplied in 2 mM solution, 2 compounds supplied in 3 mg/mL solution.
Container:
96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Storage:
-80°C
Shipping:
Blue ice
Composition

Exosomes Compound Library

Source: MedChem Express

Documentation

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    Product Name:
    Exosomes Compound Library
    Cat. No.:
    HY-L072
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    • 96-well Plate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack