1. Metabolic Enzyme/Protease
  2. Carbonic Anhydrase

Carbonic Anhydrase

Carbonic anhydrase is a zinc-containing enzyme that catalyzes the reversible hydration of carbon dioxide: CO2+H2O<-->HCO3-+H+. The enzyme is the target for drugs, such as Acetazolamide, Methazolamide, and Dichlorphenamide, for the treatment of glaucoma. There are three evolutionarily unrelated CA families, designated alpha, beta, and gamma. All known CAs from the animal kingdom are of the alpha type. There are seven mammalian CA isozymes with different tissue distributions and intracellular locations, CA I-VII.

Carbonic anhydrase is one of the core enzyme in organism, which involves in osmoregulation, ionic regulation, acid-base regulation and other physiological and biochemical process.

Carbonic Anhydrase Related Products (13):

Cat. No. Product Name Effect Purity
  • HY-B0782
    Acetazolamide Inhibitor 98.39%
    Acetazolamide is a potent carbonic anhydrase (CA) inhibitor; best-studied agent for the amelioration of acute mountain sickness (AMS).
  • HY-B0397
    Dichlorphenamide Inhibitor >98.0%
    Dichlorphenamide(Diclofenamide) is a carbonic anhydrase inhibitor that is used in the treatment of glaucoma.
  • HY-B0588
    Brinzolamide Inhibitor 99.78%
    Brinzolamide(AL 4862) is a potent carbonic anhydrase II inhibitor with IC50 of 3.19 nM.
  • HY-B0109A
    Dorzolamide hydrochloride Inhibitor 99.47%
    Dorzolamide Hcl(L671152 Hcl; MK507 Hcl) is an anti-glaucoma agent, which is a carbonic anhydrase inhibitor.
  • HY-13513
    U-104 Inhibitor 99.50%
    U-104 is a potent carbonic anhydrase (CA) inhibitor for CA IX and CA XII with Ki of 45.1 nM and 4.5 nM; low inhibition for CA I and CA II.
  • HY-B2147
    2-Aminobenzenesulfonamide Inhibitor 99.88%
    2-Aminobenzenesulfonamide is a carbonic anhydrase IX inhibitor.
  • HY-N0085
    Dimethylfraxetin Inhibitor 99.97%
    Dimethylfraxetin is a Carbonic anhydrase inhibitor, with a Ki value of 0.0097 μM.
  • HY-B1480
    Ethoxzolamide Inhibitor 98.78%
    Ethoxzolamide is a carbonic anhydrase inhibitor with Ki of 1 nM.
  • HY-B0553
    Methazolamide Inhibitor
    Methazolamide is a carbonic anhydrase inhibitor used to treat glaucoma.
  • HY-B0109
    Dorzolamide Inhibitor
    Dorzolamide(L671152; MK507) is an anti-glaucoma agent, which is a carbonic anhydrase inhibitor.
  • HY-B0782S
    Acetazolamide D3 Inhibitor
    Acetazolamide D3 is deuterium labeled Acetazolamide, which is a potent carbonic anhydrase (CA) inhibitor.
  • HY-B0483
    Tioxolone Inhibitor
    Tioxolone, a metalloenzyme carbonic anhydrase I inhibitor, is an anti-acne preparation.
  • HY-108316
    Sultiame Inhibitor 99.11%
    Sultiame is a carbonic anhydrase inhibitor, widely used as an antiepileptic drug.