Carbonic anhydrase inhibitor 16
Based on 1 Customer Validation
Carbonic anhydrase inhibitor 16 (compound 1) is a dengue protease inhibitor with inhibitory activity against carbonic anhydrase hCA I and hCA II (Ki: 28.5 nM, 2.2 nM).
For research use only. We do not sell to patients.
- Purity: 98.00%
- CAS No.: 4479-70-3
- Formula: C14H10N2O4S
- Molecular Weight:302.31
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Ki: 28.5 nM (hCA I), 2.2 nM (hCA II)[1]
Chemical Information
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CAS No. 4479-70-3
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Appearance Solid
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Molecular Weight 302.31
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Formula C14H10N2O4S
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Color White to off-white
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SMILES
O=C1N(C2=CC=C(S(N)(=O)=O)C=C2)C(C3=C1C=CC=C3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (330.79 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3079 mL | 16.5393 mL | 33.0786 mL | 82.6966 mL |
| 5 mM | 0.6616 mL | 3.3079 mL | 6.6157 mL | 16.5393 mL | |
| 10 mM | 0.3308 mL | 1.6539 mL | 3.3079 mL | 8.2697 mL | |
| 15 mM | 0.2205 mL | 1.1026 mL | 2.2052 mL | 5.5131 mL | |
| 20 mM | 0.1654 mL | 0.8270 mL | 1.6539 mL | 4.1348 mL | |
| 25 mM | 0.1323 mL | 0.6616 mL | 1.3231 mL | 3.3079 mL | |
| 30 mM | 0.1103 mL | 0.5513 mL | 1.1026 mL | 2.7566 mL | |
| 40 mM | 0.0827 mL | 0.4135 mL | 0.8270 mL | 2.0674 mL | |
| 50 mM | 0.0662 mL | 0.3308 mL | 0.6616 mL | 1.6539 mL | |
| 60 mM | 0.0551 mL | 0.2757 mL | 0.5513 mL | 1.3783 mL | |
| 80 mM | 0.0413 mL | 0.2067 mL | 0.4135 mL | 1.0337 mL | |
| 100 mM | 0.0331 mL | 0.1654 mL | 0.3308 mL | 0.8270 mL |