Signaling Pathway

RSV

RSV

Related Products

PDF File 0.24MB

Human respiratory syncytial virus (RSV) is a virus that causes respiratory tract infections. RSV is a negative-sense, single-stranded RNA virus of the family Paramyxoviridae, which includes common respiratory viruses such as those causingmeasles and mumps. RSV is a member of the paramyxovirus subfamily Pneumovirinae. RSV is a major cause of lower respiratory tract infections and hospital visits during infancy and childhood.

RSV Inhibitors & Modulators (8)

Product Name Catalog No. Brief Description
ALS-8112

HY-12983

ALS-8112 is a potent, selective RSV polymerase inhibitor, exhibits the most promising activity in the RSV replicon assay with an EC50 of 0.15 μM.

ALS-8176

HY-12983A

ALS-8176 is a first-in-class RSV polymerase inhibitor for treatment of human respiratory syncytial virus infection.

Presatovir

HY-16727

Presatovir is a novel, orally bioavailable RSV fusion inhibitor, against a wide range of RSV A and B clinical isolates (mean EC50 = 0.43 nM).

Ribavirin

HY-B0434

Ribavirin is a nucleoside antimetabolite antiviral agent that blocks nucleic acid synthesis and is used against both RNA and DNA viruses.

RSV604

HY-12993

RSV604 is a novel inhibitor of respiratory syncytial virus replication(EC50=0.86 uM); a putative RSV nucleoprotein(N) inhibitor in phase 2 clinical trials.

RSV604 R enantiomer

HY-12993B

RSV604 R enantiomer is the R-enantiomer of RSV604.

RSV604 racemate

HY-12993A

RSV604 racemate is a racemic mixture, shows less potency against strains of respiratory syncytial virus (RSV) than the S-isomer.

TMC353121

HY-11097

TMC353121 is a potent RSV fusion inhibitor with pEC50 of 9.9(t1/2 in lung = 25 h).