1. Recombinant Proteins
  2. Cytokines and Growth Factors
  3. TNF Superfamily

Tumour necrosis factor (TNF) is a major inflammatory cytokine produced by immune cells. TNF (TNF-α) was first identified for its ability to causes necrosis of tumors. TNF-α is mainly produced by macrophages, whereas TNF-β is mainly produced by T lymphocytes. TNF plays important roles in diverse cellular events such as cell survival, proliferation, differentiation, and death. The tumor necrosis factor (TNF) superfamily is currently composed of 19 structurally related cytokines of the TNF superfamily (TNFSF) and 29 their receptors (TNF receptor superfamily, TNFRSF). TNF superfamily ligands are trimeric type II transmembrane proteins characterized by a conserved C-terminal TNF homology domains (THD). TNF-superfamily members induce apoptosis, proliferation, survival or differentiation at the cellular level.

Cat. No. Product Name / Synonyms Species Source
  • HY-P70536
    TNF RII/TNFRSF1B Protein, Human (183a.a, HEK293, mFc)

    TNF-RII; TNFRII; TNF RII; Tumor necrosis factor receptor superfamily member 1B; TNFRSF1B; Tumor necrosis factor receptor 2; TNF-R2; Tumor necrosis factor receptor type II; p75; p80 TNF-alpha receptor; CD120b

    Human HEK 293
  • HY-P72423
    TRAIL R2/TNFRSF10B Protein, Human (Biotinylated, HEK293, Avi-His)

    TNF-Related Apoptosis-Inducing Ligand Receptor 2; TRAIL Receptor 2; TRAIL-R2; CD262; TNFRSF10B; DR5; KILLER; TRICK2; ZTNFR9

    Human HEK 293
  • HY-P75639
    CD30 Ligand/TNFSF8 Protein, Rat (HEK293)

    TNF superfamily member 8; CD153; CD30 Ligand; TNFSF8

    Rat HEK 293
  • HY-P75640
    CD30 Ligand/TNFSF8 Protein, Rat (HEK293, Fc)

    TNF superfamily member 8; CD153; CD30 Ligand; TNFSF8

    Rat HEK 293
  • HY-P7058
    TNF-alpha/TNFSF2 Protein, Human

    rHuTNF-α/TNFSF2; TNF-alpha; Cachectin; DIF; TNFA; Differentiation-inducing factor

    Human E. coli
    TNF-alpha/TNFSF2 Protein, Human is a strong pro-inflammatory cytokine, exhibits high efficacy and tumor cell targeting capability, with low toxicity effects on healthy cells.
  • HY-P7306
    TRAIL/Apo2L Protein, Human

    rHuTRAIL/Apo2L; TNFSF10; CD253

    Human E. coli
    TRAIL/Apo2L Protein, Human is a protein functioning as a ligand that induces the process of apoptosis through engagement of death receptors.
  • HY-P7090
    TNF-alpha/TNFSF2 Protein, Mouse (156a.a)

    rMuTNF-α/TNFSF2; TNF-alpha; Cachectin; DIF; TNFA; Differentiation-inducing factor

    Mouse E. coli
    TNF-alpha/TNFSF2 Protein, Mouse (156a.a) is a strong pro-inflammatory cytokine, effective in the immune system during inflammation, cell proliferation, differentiation and apoptosis.
  • HY-P7108
    TNF-alpha/TNFSF2 Protein, Rat (P.pastoris)

    rRtTNF-α/TNFSF2; TNF-alpha; Cachectin; DIF; TNFA; Differentiation-inducing factor

    Rat P. pastoris
    TNF-alpha/TNFSF2 Protein, Rat (P.pastoris) is a strong pro-inflammatory cytokine, effective in the immune system during inflammation, cell proliferation, differentiation and apoptosis.
  • HY-P7090A
    TNF-alpha/TNFSF2 Protein, Mouse (P.pastorisd)

    rMuTNF-α/TNFSF2; TNF-alpha; Cachectin; DIF; TNFA; Differentiation-inducing factor

    Mouse P. pastoris
    TNF-alpha/TNFSF2 Protein, Mouse (P.pastorisd) is a strong pro-inflammatory cytokine, effective in the immune system during inflammation, cell proliferation, differentiation and apoptosis.
  • HY-P70821
    TRAIL Protein, Mouse (HEK 293, Fc)

    Tumor necrosis factor receptor superfamily member 10B/Death receptor 5/MK/CD262/Tnfrsf10b/Dr5/Killer

    Mouse HEK293
  • HY-P7416
    TNF-alpha/TNFSF2 Protein, Human (His)

    rHuTNF-α, His; Cachectin; TNFSF2

    Human E. coli
    TNF-alpha/TNFSF2 Protein, Human (His) is recombinant human tumor necrosis factor alpha (TNF-α) with his tag. TNF-alpha/TNFSF2 Protein, a pleiotropic cytokine, is one of the major mediators of inflammation and is involved in a number of infectious and parasitic diseases. It appears to be involved in blood-brain barrier, inflammatory, thrombogenic, and vascular changes associated with brain injury.
  • HY-P7425
    RANK L/TNFSF11 Protein, Mouse

    rMuRANK L/TNFSF11; TRANCE; CD254

    Mouse E. coli
    RANK L/TNFSF11 Protein, Mouse is a TNF-related activation-induced cytokine produced in E. coli. Mouse and human RANK Ligand share 85% amino acid identity. RANK L/TNFSF11 Protein induces the activation of the c-jun N terminal kinase, enhances T cell growth and dendritic cell function, induces osteoclastogenesis, and lymph node organogenesis.
  • HY-P7089
    TRAIL/TNFSF10 Protein, Mouse (His)

    rMuTRAIL/TNFSF10; TNF-related apoptosis-inducing ligand; Tumor necrosis factor ligand superfamily member 10

    Mouse E. coli
    TRAIL/TNFSF10 Protein, Mouse, also called Apo2L, is a member of the tumor necrosis factor (TNF) family of ligands which can innitiate apoptosis through engagement of its death receptors.
  • HY-P73388
    RANKL Protein, Mouse (HEK293, Fc)

    Tumor necrosis factor ligand superfamily member 11; RANKL; CD254; ODF; OPGL; TNFSF11; TRANCE

    Mouse HEK293
  • HY-P73386
    RANKL Protein, Human (HEK293)

    Tumor necrosis factor ligand superfamily member 11; RANKL; CD254; ODF; OPGL; TNFSF11; TRANCE

    Human HEK293
  • HY-P7425A
    RANK L/TNFSF11 Protein, Mouse (CHO, His)

    rMuRANK L/TNFSF11, His; TRANCE; CD254

    Mouse CHO
    RANK L/TNFSF11 Protein, Mouse (CHO, His) is a TNF-related activation-induced cytokine produced in CHO. Mouse and human RANK Ligand share 85% amino acid identity. RANK L/TNFSF11 Protein, Mouse (CHO, His) induces the activation of the c-jun N terminal kinase, enhances T cell growth and dendritic cell function, induces osteoclastogenesis, and lymph node organogenesis.
  • HY-P7417
    TNF-alpha/TNFSF2 Protein, Mouse (His)

    rMuTNF-α, His; Cachectin; TNFSF2

    Mouse E. coli
    TNF-alpha/TNFSF2 Protein, Mouse (His) is recombinant mouse tumor necrosis factor alpha (TNF-α) with his tag. TNF-alpha/TNFSF2 Protein, a major mediator of inflammation, is involved in a number of infectious and parasitic diseases.
  • HY-P70801
    TNFRSF1A Protein, Human (His)

    Tumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor 1; TNF-R1; Tumor necrosis factor receptor type I; TNF-RI; TNFR-I; TNFAR; TNFR1

    Human E. coli
  • HY-P70816
    BAFF/TNFSF13B Protein, Mouse (HEK 293, His)

    Tumor necrosis factor ligand superfamily member 13B; B lymphocyte stimulator; BLyS; B-cell-activating factor; BAFF; Dendritic cell-derived TNF-like molecule; TNF- and APOL-related leukocyte expressed ligand 1; TALL-1

    Mouse HEK293
  • HY-P70571
    TNF-alpha/TNFSF2 Protein, Mouse (147a.a)

    Tumor Necrosis Factor; Cachectin; TNF-Alpha; Tumor Necrosis Factor Ligand Superfamily Member 2; TNF-a; Tumor Necrosis Factor; Membrane Form; Tumor Necrosis Factor; Soluble Form; Tnf; Tnfa; Tnfsf2

    Mouse E. coli
Cat. No. Product Name Effect Purity