CD336/NCR2
CD336 is NKp44, encoded by NCR2, an activating natural cytotoxicity receptor that distinguishes activated NK cells from resting ones and is additionally found on a subset of innate lymphoid cells. Its extracellular region comprises a V-set Ig-like domain plus a stalk, and the transmembrane lysine couples the receptor to the ITAM-bearing adaptor DAP12 for activating signaling. NKp44 recognizes viral hemagglutinins, contributing to influenza antiviral responses, and has been reported to interact with tumor-associated ligands and with PD-1 on activated T cells, an interaction implicated in immunosuppression. CD336 expression is a standard activation marker in NK cell monitoring.
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CD336/NCR2 Recombinant Proteins (3)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
