CD85e/LILRA3
CD85e, also known as LILRA3, is a member of the activating leukocyte immunoglobulin-like receptor group encoded within the LILR cluster on chromosome 19. Uniquely among its siblings, LILRA3 lacks a transmembrane region and is secreted as a soluble protein, carrying six extracellular immunoglobulin-like domains, the longest extracellular region in the family, although its precise ligand remains undefined. Expression is high in monocytes and inflamed tissues, and gene variants have been associated with Sjögren syndrome and multiple sclerosis. Lacking a signaling cytoplasmic tail, LILRA3 is thought to modulate myeloid responses by sequestering ligands or engaging partner receptors.
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CD85e/LILRA3 Recombinant Proteins (3)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
