1. One-stop Drug Screening
  2. Screening Libraries
  3. Bioactive Compound Series
  4. According to Signaling Pathway or Protein Family
  5. Membrane Receptor-targeted Compound Library
Membrane Receptor-targeted Compound Library

Cat. No.: HY-L150

Membrane receptors, also known cell surface receptors or transmembrane receptors, are transmembrane proteins embedded into the plasma membrane which play an essential role in maintaining communication between the internal processes within the cell and various types of extracellular signals. They act in cell signaling by receiving (binding to) extracellular molecules, which are also called ligands. These extracellular molecules include hormones, cytokines, growth factors, neurotransmitters, lipophilic signaling molecules such as prostaglandins, and cell recognition molecules.

There are three kinds of membrane receptors: ion channel-linked receptors, enzyme-linked receptors and G-protein-linked receptors. They play important roles in keeping human normal physiologic processes. GPCRs and ion channels are important drug targets in drug discovery.

MCE provides a unique collection of 4,734 compounds targeting a variety of membrane receptors. MCE Membrane reeptor-targeted Compound Library can be used for membrane receptor-focused screening and drug discovery.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
- +

Compound Screening Libraries

Top Publications Citing Use of MedChemExpress (MCE) Products

Publications Citing Use of MedChemExpress (MCE) Products

  • Biological Activity
  • Product Details
  • Documentation
  • Composition

Description & Advantages

•   A unique collection of 4,734 small molecules targeting variety of membrane receptors.

•    Targets such as FGFR, TRP Channel, VEGFR, TNF Receptor, Opioid Receptor, 5-HT Receptor, ion channel, etc.

•   All of the small molecules in this library are well characterized with biological and pharmaceutical activity. Some compounds have been approved by the FDA.

•    A powerful tool for discovering membrane receptor-based drugs.

•   Structurally diverse, medicinally active, and cell permeable.

•   NMR and HPLC validated to ensure the highest purity.

•   All compounds are in stock and continuously updated.

Product Details


A collection of 4,734 membrane receptor-related compounds supplied as pre-dissolved Solutions or Solid.
Solution: 4,663 compounds supplied in 10 mM solution, 66 compounds supplied in 2 mM solution, 5 compounds supplied in 3 mg/mL solution.


96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.


96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode.




Blue ice or dry ice


EGFR (196)

iGluR (157)

VEGFR (155)

mAChR (152)

mGluR (122)

nAChR (100)

Ras (100)

FGFR (85)

PDGFR (84)

CCR (61)

Raf (56)

CXCR (51)

c-Kit (46)

FLT3 (35)

CFTR (34)

HIV (32)

RET (32)

GCGR (29)

ERK (26)

Akt (25)

Src (24)

COX (21)

SGLT (21)

GLUT (19)

CaSR (17)

BCRP (16)

PPAR (16)

GHSR (15)

Related Service
Compound Customization
  •  Specific Compounds
  •  Quantities
  •  Plate Map
  •  Concentration
  •  Form (Solid or Solution)
  •  YES
Contact Us for Customization

Your information is safe with us. * Required Fields.

Product Name



Applicant Name *


Email Address *

Phone Number *


Organization Name *

Department *


Requested quantity *

Country or Region *


Container *


    Inquiry Information

    Product Name:
    Membrane Receptor-targeted Compound Library
    Cat. No.:
    MCE Japan Authorized Agent:

    Request SDF File

    Please enter your email address. We will send your requested SDF file to you as soon as possible.

    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack