2. Isotope-Labeled Compounds
  3. Isotope-Labeled Metabolites

Isotope-Labeled Metabolites

Metabolites are intermediates or end products of metabolism that have various functions. The term metabolite is usually used for small molecules. MedChemExpress ( MCE ) offers an extensive range of Stable Isotope-Labeled Metabolites, including drug metabolites, endogenous metabolites, carnitine/acylcarnitines, cholines, neurotransmitters, lipids, organic acids and derivatives etc to assist metabolomics.

Isotope-Labeled Metabolites (570):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B0389A
    D-Glucose-13C6 110187-42-3 ≥99.0%
    D-Glucose-13C6 is a tracer used to trace glucose-related synthetic catabolism, is a low-cost alternative with the significant advantage that the sixth isotope of natural glucose has virtually zero natural abundance, which facilitates isotopomer analysis with <1% labeled glucose in the infusate[1][2].
    D-Glucose-<sup>13</sup>C<sub>6</sub>
  • HY-N0390S1
    L-Glutamine-13C5 184161-19-1 ≥98.0%
    L-Glutamine-13C5 is the 13C-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
    L-Glutamine-<sup>13</sup>C<sub>5</sub>
  • HY-W050026S
    Phenylacetylglutamine-d5 1331909-01-3 98.01%
    Phenylacetylglutamine-d5 is the deuterium labeled Phenylacetylglutamine. Phenylacetylglutamine is a colonic microbial metabolite from amino acid fermentation[1].
    Phenylacetylglutamine-d<sub>5</sub>
  • HY-B1204S
    Histamine-α,α,β,β-d4 (dihydrochloride) 344299-48-5 ≥98.0%
    Histamine-α,α,β,β-d4 (dihydrochloride) is the deuterium labeled Histamine. Histamine is an organic nitrogenous compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.
    Histamine-α,α,β,β-d<sub>4</sub> (dihydrochloride)
  • HY-N7092S
    D-Fructose-13C6 201595-65-5 ≥98.0%
    D-Fructose-13C6 is the 13C labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants.
    D-Fructose-<sup>13</sup>C<sub>6</sub>
  • HY-W021448S1
    Glycocyamine-15N,13C2 2483829-93-0
    Glycocyamine-15N,13C2 is the 13C and 15N labeled Glycocyamine[1]. Glycocyamine (Guanidinoacetic acid), a precursor of creatine, is a replacement of dietary arginine and could support overall energy homeostasis of the bird[2].
    Glycocyamine-<sup>15</sup>N,<sup>13</sup>C<sub>2</sub>
  • HY-126182S4
    Desacetyl Diltiazem-d4 (hydrochloride)
    Desacetyl Diltiazem-d4 (hydrochloride) is the deuterium labeled Desacetyl Diltiazem hydrochloride[1].
    Desacetyl Diltiazem-d<sub>4</sub> (hydrochloride)
  • HY-B0520AS1
    Benztropine-d3 (mesylate) 202529-16-6
    Benztropine-d3 (mesylate) is the deuterium labeled Benztropine mesylate[1]. Benztropine mesylate (Benzatropine mesylate) is an orally active centrally acting anticholinergic agent that can be used for Parkinson's disease research. Benztropine mesylate is an anti-histamine agent and a dopamine re-uptake inhibitor. Benztropine mesylate is also a human D2 dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects[2][3].
    Benztropine-d<sub>3</sub> (mesylate)
  • HY-113147AS
    L-Palmitoylcarnitine-d3 (hydrochloride) 1334532-26-1 99.83%
    L-Palmitoylcarnitine-d3 (hydrochloride) is the deuterium labeled L-Palmitoylcarnitine hydrochloride. L-Palmitoylcarnitine hydrochloride, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine hydrochloride inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2[1].
    L-Palmitoylcarnitine-d<sub>3</sub> (hydrochloride)
  • HY-B0282S1
    Acetylcholine-d9 (chloride) 344298-95-9 ≥99.0%
    Acetylcholine-d9 (chloride) is the deuterium labeled Acetylcholine chloride. Acetylcholine chloride (ACh chloride), a neurotransmitter, is a potent cholinergic agonist. Acetylcholine chloride is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs)[1][2]. Acetylcholine chloride inhibits p53 mutant peptide aggregation in vitro[5].
    Acetylcholine-d<sub>9</sub> (chloride)
  • HY-113468AS
    3-O-Methyldopa-d3 586954-09-8 99.34%
    3-O-Methyldopa-d3 is deuterium labeled 3-O-Methyldopa. 3-O-Methyldopa is a metabolite of L-DOPA which is formed by catechol-O-methyltransferase (COMT). 3-O-Methyldopa competitively inhibits the pharmacodynamics of l-DOPA and dopamine[1].
    3-O-Methyldopa-d<sub>3</sub>
  • HY-N0390S
    L-Glutamine-15N 80143-57-3 ≥98.0%
    L-Glutamine-15N is the 15N-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
    L-Glutamine-<sup>15</sup>N
  • HY-N0384S2
    Homovanillic acid-d5 53587-32-9
    Homovanillic acid-d5 is the deuterium labeled Homovanillic acid. Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency.
    Homovanillic acid-d<sub>5</sub>
  • HY-12772S
    Hydroxy Itraconazole-d8 99.71%
    Hydroxy Itraconazole-d8 is the deuterium labeled Hydroxy Itraconazole. Hydroxy Itraconazole is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.
    Hydroxy Itraconazole-d<sub>8</sub>
  • HY-B0504S
    Creatinine-d3 143827-20-7 ≥99.0%
    Creatinine-d3 is a deuterium labeled Creatinine. Creatinine is a break-down product of creatine phosphate in muscle[1].
    Creatinine-d<sub>3</sub>
  • HY-B0282S
    Acetylcholine-d4 (chloride) 344298-94-8 99.21%
    Acetylcholine-d4 (chloride) is the deuterium labeled Acetylcholine chloride. Acetylcholine chloride (ACh chloride), a neurotransmitter, is a potent cholinergic agonist. Acetylcholine chloride is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs)[1][2]. Acetylcholine chloride inhibits p53 mutant peptide aggregation in vitro[5].
    Acetylcholine-d<sub>4</sub> (chloride)
  • HY-133689AS
    3-Nitrophenylhydrazine-13C6 (hydrochloride) 1977535-33-3 98.26%
    3-Nitrophenylhydrazine-13C6 (hydrochloride) is the 13C labeled 3-Nitrophenylhydrazine hydrochloride[1].
    3-Nitrophenylhydrazine-<sup>13</sup>C<sub>6</sub> (hydrochloride)
  • HY-104026S
    L-Kynurenine-d4 2672568-86-2 ≥99.0%
    L-Kynurenine-d4 is the deuterium labeled L-Kynurenine. L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist[1][2].
    L-Kynurenine-d<sub>4</sub>
  • HY-B0389S10
    D-Glucose-13C 101615-88-7 ≥99.0%
    D-Glucose-13C is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].
    D-Glucose-<sup>13</sup>C
  • HY-103395S
    Methylmalonic acid-d3 42522-59-8 ≥98.0%
    Methylmalonic acid-d3 is the deuterium labeled Methylmalonic acid. Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer[1][2].
    Methylmalonic acid-d<sub>3</sub>