1. Signaling Pathways
  2. PI3K/Akt/mTOR
  3. mTOR
  4. mTORC1 Inhibitors

mTORC1 Inhibitors

mTOR

mTORC1

mTORC2

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform mTORC1 together.

Please try each isoform separately.

mTORC1 Specific Inhibitors & Activators
Product Name mTORC1 mTOR mTORC2 mTORC1 Selectivity Purity
Rapamycin
mTOR, IC50: 0.1 nM (in HEK293 cells )
    Selective Inhibitor 99.93%
Everolimus
mTOR, IC50: 5-6 nM
    Selective Inhibitor 98.79%
Temsirolimus
mTOR, IC50: 1.76 μM
    Selective Inhibitor 99.56%
Deforolimus
mTOR
    Selective Inhibitor 98.46%
L-Leucine
mTORC1
    Selective Activator >98.0%
DL001
mTORC1, IC50: 74.9 pM
    Selective Inhibitor
MHY1485
mTORC1
 
mTORC2
Pan Activator 99.05%
PI-103
mTORC1, IC50: 20 nM
 
mTORC2, IC50: 83 nM
Pan Inhibitor 99.86%
Torkinib
mTORC1, IC50: 30 nM
mTOR, IC50: 8 nM
mTORC2, IC50: 58 nM
Pan Inhibitor 95.47%
Omipalisib
mTORC1, Ki: 0.18 nM
 
mTORC2, Ki: 0.3 nM
Pan Inhibitor 99.31%
OSI-027
mTORC1, IC50: 22 nM
mTOR, IC50: 4 nM
mTORC2, IC50: 65 nM
Pan Inhibitor 99.40%
PI-103 Hydrochloride
mTORC1, IC50: 20 nM
 
mTORC2, IC50: 83 nM
Pan Inhibitor 99.78%
Voxtalisib
mTORC1, IC50: 160 nM
mTOR, IC50: 157 nM
mTORC2, IC50: 910 nM
Pan Inhibitor 98.93%
PQR620
mTORC1
 
mTORC2
Pan Inhibitor 98.06%
Palomid 529
TORC1
 
TORC2
Pan Inhibitor 99.42%
(+)-Usnic acid
mTORC1
 
mTORC2
Pan Inhibitor
FT-1518
mTORC1
 
mTORC2
Pan Inhibitor
PQR-530
mTORC1
 
mTORC2
Pan Inhibitor