1009298-09-2
1009298-09-2
Chemical Structure
AZD-8055
- CAS No.: 1009298-09-2
- Formula:C25H31N5O4
- Molecular Weight:465.54
IUPAC Name: (5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol
InChIKey: KVLFRAWTRWDEDF-IRXDYDNUSA-N
SMILES: OCC1=CC(C2=NC3=NC(N4CCOC[C@@H]4C)=NC(N5[C@@H](C)COCC5)=C3C=C2)=CC=C1OC
Biological Activity: AZD-8055 is a potent, selective, and orally bioavailable ATP-competitive mTOR kinase inhibitor with an IC50 of 0.8 nM. AZD-8055 inhibits both mTORC1 and mTORC2[1].
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AZD-8055 | 99.60% | AZD-8055 is a potent, selective, and orally bioavailable ATP-competitive mTOR kinase inhibitor with an IC50 of 0.8 nM. AZD-8055 inhibits both mTORC1 and mTORC2. | ||||||||||||||||||||
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AZD-8055 (Standard) | ≥98% | AZD-8055 (Standard) is the analytical standard of AZD-8055 (HY-10422). This product is intended for research and analytical applications. AZD-8055 is a potent, selective, and orally bioavailable ATP-competitive mTOR kinase inhibitor with an IC50 of 0.8 nM. AZD-8055 inhibits both mTORC1 and mTORC2. | ||||||||||||||||||||
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References
Keywords
