1. Recombinant Proteins
  2. CD Antigens
  3. NK Cell CD Proteins
  4. CRTAM/CD355
Cat. No. Product Name / Synonyms Species Source
  • HY-P7855
    CRTAM/CD355 Protein, Human (HEK293, His)

    rHuCytotoxic and regulatory T-cell molecule/CRTAM, His; Cytotoxic and Regulatory T-Cell Molecule; Class-I MHC-Restricted T-Cell-Associated Molecule; CD355; CRTAM

    Human HEK293
    The CRTAM/CD355 protein is a key mediator of heterophilic intercellular adhesion and complexly regulates the activation, differentiation, and tissue retention of T cell subsets. Its interaction with CADM1 promotes NK cell cytotoxicity and CD8+ T cell secretion of IFNG, thus contributing to NK cell-mediated tumor rejection. CRTAM/CD355 Protein, Human (HEK293, His) is the recombinant human-derived CRTAM/CD355 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CRTAM/CD355 Protein, Human (HEK293, His) is 269 a.a., with molecular weight of 58-64 kDa.
  • HY-P77636
    CRTAM/CD355 Protein, Cynomolgus (HEK293, Fc)

    CD355 antigen; CD355; CRTAM

    Cynomolgus HEK293
    CRTAM/CD355 protein regulates T-cell subsets by mediating cell-cell adhesion. It interacts with CADM1 to enhance NK cell cytotoxicity, IFNG secretion by CD8+ T-cells, and NK cell-mediated tumor rejection. CRTAM regulates CD8+ T-cell proliferation but not cytotoxicity. It also promotes CD4+ T-cell polarization and regulates TCR-mediated proliferation and cytokine production. CRTAM contributes to the retention of activated CD8+ T-cells in lymph nodes and intestinal retention of intraepithelial T-cells. It may exist as a monomer or homodimer and interacts with SCRIB to promote polarization in CD4+ T-cells. CRTAM/CD355 Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived CRTAM/CD355 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CRTAM/CD355 Protein, Cynomolgus (HEK293, Fc) is 270 a.a., with molecular weight of 70-80 kDa.
  • HY-P77907
    CRTAM/CD355 Protein, Mouse (HEK293, His)

    CD355 antigen; CD355; CRTAM

    Mouse HEK293
    CRTAM/CD355 protein regulates T cell subsets by mediating cell-cell adhesion. It interacts with CADM1 to enhance NK cell cytotoxicity, IFNG secretion by CD8+ T cells, and NK cell-mediated tumor rejection. CRTAM/CD355 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CRTAM/CD355 protein, expressed by HEK293 , with C-His labeled tag. The total length of CRTAM/CD355 Protein, Mouse (HEK293, His) is 273 a.a., with molecular weight of 60-70 kDa.
  • HY-P7807
    CRTAM/CD355 Protein, Cynomolgus (HEK293, His)

    rCynCRTAM, His; Cytotoxic and Regulatory T-Cell Molecule; Class-I MHC-Restricted T-Cell-Associated Molecule; CD355; CRTAM

    Cynomolgus HEK293
    CRTAM/CD355 Protein is an immunoglobulin-superfamily transmembrane protein, and is a member of nectin-like protein superfamily. CRTAM is also expressed on activated human NK cells, CD8+ T cells and a subset of CD4+ T cells. CRTAM takes part in cellular adhesion, polarity, and proliferation. CRTAM also regulates lymphocyte function, and promotes TCD8+ cell adhesion and retention within the lymph node. Furthermore, CRTAM can interact with Necl-2, and promotes cytotoxicity of NK cells and IFN-γ secretion of CD8+ T cells in vitro, and NK cell-mediated rejection of tumors expressing Necl-2 in vivosup>[3]. CRTAM/CD355 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived CRTAM/CD355 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CRTAM/CD355 Protein, Cynomolgus (HEK293, His) is 270 a.a., with molecular weight of 50-60 kDa.
  • HY-P700700
    CRTAM/CD355 Protein, Canine (HEK293, His)

    CD355 antigen; CD355; CRTAM

    Canine HEK293
    The CRTAM/CD355 protein is a key mediator of heterophilic intercellular adhesion and complexly regulates the activation, differentiation, and tissue retention of T cell subsets. Its interaction with CADM1 promotes NK cell cytotoxicity and CD8+ T cell secretion of IFNG, thus contributing to NK cell-mediated tumor rejection. CRTAM/CD355 Protein, Canine (HEK293, His) is the recombinant canine-derived CRTAM/CD355 protein, expressed by HEK293 , with C-His labeled tag. The total length of CRTAM/CD355 Protein, Canine (HEK293, His) is 270 a.a., with molecular weight of 55-70 kDa.
Cat. No. Product Name Effect Purity