2. Recombinant Proteins
  3. CD Antigens Complement System
  4. Platelet CD Proteins Epithelial cell CD Proteins Endothelial cell CD Proteins Complement Regulatory Proteins
  5. Membrane Cofactor Protein/CD46

Membrane Cofactor Protein/CD46

Recombinant Protein Expression Service

Membrane Cofactor Protein/CD46

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Cat. No. Product Name / Synonyms Species Source
  • HY-P72020
    CD46 Protein, Human (HEK293, hFc)

    AHUS2; Antigen defined by monoclonal TRA 2 10; Antigen identified by monoclonal TRA 2 10; CD46; TRA2.10

    		Human HEK293
    CD46 Protein serves as a cofactor for complement factor I, safeguarding cells against complement-induced harm. It aids in sperm-oocyte fusion and acts as a T-cell costimulatory factor, facilitating the formation of T-regulatory 1 cells. These cells secrete interleukin-10, suppressing immune responses and preventing autoimmunity. Pathogens can exploit CD46's immune regulation abilities to induce an immunosuppressive state in T-cells. CD46 Protein, Human (HEK293, hFc) is the recombinant human-derived CD46 protein, expressed by HEK293, with C-hFc labeled tag. The total length of CD46 Protein, Human (HEK293, hFc) is 294 a.a., with molecular weight of ~70.0 kDa.
  • HY-P72723
    CD46 Protein, Human (HEK293, His)

    Membrane Cofactor Protein; TLX; CD46; MCP; MIC10

    		Human HEK293
    CD46 protein is an important cofactor for complement factor I, a serine protease that protects autologous cells by cleaving deposited C3b and C4b. In addition to complement regulation, CD46 is involved in sperm-oocyte fusion during fertilization. CD46 Protein, Human (HEK293, His) is the recombinant human-derived CD46 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD46 Protein, Human (HEK293, His) is 294 a.a., with molecular weight of 50-65 kDa.
  • HY-P700681
    CD46 Protein, Cynomolgus (HEK293, His)

    TLX; CD46; MCP; MIC10; AHUS2; TRA2.10

    		Cynomolgus HEK293
    CD46 protein acts as a crucial cofactor for complement factor I, a serine protease protecting autologous cells by cleaving deposited C3b and C4b. In addition to complement regulation, CD46 is involved in sperm-oocyte fusion during fertilization. Acting as a costimulatory factor for T-cells, it promotes the differentiation of CD4+ cells into T-regulatory 1 cells, crucial for immune modulation by secreting interleukin-10, suppressing immune responses, and preventing autoimmunity. CD46 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived CD46 protein, expressed by HEK293, with C-His labeled tag. The total length of CD46 Protein, Cynomolgus (HEK293, His) is 295 a.a., with molecular weight of 50-70 kDa.
  • HY-P700680
    CD46 Protein, Canine (HEK293, His)

    TLX; CD46; MCP; MIC10; AHUS2; TRA2.10; Membrane cofactor; LOC609365

    		Canine HEK293
    CD46 protein does not possess the conserved residue(s) necessary for propagating feature annotation. CD46 Protein, Canine (HEK293, His) is the recombinant canine-derived CD46 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD46 Protein, Canine (HEK293, His) is 300 a.a., with molecular weight of 50-70 kDa.
Cat. No. Product Name Effect Purity