Mass Spectrometry Human Endogenous Metabolite Library

83 Cited Publications
Customer Review

Based on 83 publication(s) in Google Scholar

Metabolomics is the large-scale study of cellular metabolic complement, with proven utility in both basic and applied studies of plants, microorganisms, and mammals. As an important tool for the study of complex biological systems, metabolomics monitors the complex molecular networks that exist in the natural flow of information from genes to mRNA and proteins to organisms. The metabolome is composed of biomolecules that most closely resemble the phenotype of an organism, and changes in its composition can easily lead to the production of diseases. Therefore, metabolomics has received much attention in drug target discovery, drug response and translational research of disease mechanisms. Mass spectrometry-based metabolomics methods can simultaneously detect and quantify thousands of metabolite signatures, thereby characterizing the pathophysiological mechanisms of various biomedical symptoms.

MCE can provide 666 mass spectrometry human endogenous metabolites that can be used for metabolite identification and quantification, functional cell detection and phenotypic screening of mass spectrometry.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

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Description & Advantages

•   A unique collection of 666 mass spectrometry human endogenous metabolites for high throughput screening (HTS) and high content screening (HCS).

•   A useful tool for metabolomics analysis.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some compounds have been approved by FDA.

•   Structurally diverse, bioactive, and cell permeable.

•   More detailed compound information with structure, IC50, and brief introduction.

•   NMR and HPLC validated ensure high purity.

•   All compounds are in stock and continuously updated.

Product Details

Formulation

A collection of 666 mass spectrometry human endogenous metabolites supplied as pre-dissolved Solutions or Solid

Solution: 647 compounds supplied in 10 mM solution, 17 compounds supplied in 2 mM solution, 2 compounds supplied in 3 mg/mL solution.

Layout

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates.
This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage
-80°C
Shipping
Blue ice or dry ice

Documentation

  • PDF
  • Excel
  • SDF
  • Manual

Composition

Apoptosis (69)

Bacterial (35)

Autophagy (21)

NF-κB (18)

Caspase (13)

ERK (13)

iGluR (12)

Fungal (11)

p38 MAPK (11)

Akt (10)

AMPK (7)

HSV (6)

MOFs (6)

mTOR (6)

STAT (6)

COX (5)

FXR (5)

JNK (5)

mGluR (5)

Parasite (5)

Sirtuin (5)

HIV (4)

JAK (4)

Mitophagy (4)

PPAR (4)

SOD (4)

GPR35 (3)

Liposome (3)

MMP (3)

nAChR (3)

PARP (3)

PI3K (3)

BCL6 (2)

CXCR (2)

Galectin (2)

Hedgehog (2)

LXR (2)

MAP3K (2)

MDM-2/p53 (2)

Organoid (2)

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200 mg
USD 120
In-stock
Estimated to ship on August 31 More
500 mg
Get Quote
Consult sales personnel for more information
Bulk Inquiry
500 mg
Get Quote
Consult sales personnel for more information
Bulk Inquiry
Estimated to ship on August 31 More