2. Signaling Pathways
  3. Others
  4. MOFs

MOFs

Metal-Organic Frameworks

MOFs (Metal-Organic Frameworks) have significant applications in biomedicine, such as serving as drug carriers for targeted delivery and controlled release to enhance therapeutic efficacy and reduce side effects. They are also used in bioimaging, disease diagnosis, and catalytic therapies (e.g., for cancer treatment).

MOFs Related Products (3079):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-100202
    TPEN
    		99.91%
    TPEN (TPEDA) is a specific cell-permeable heavy metal chelator. TPEN has a higher affinity for Zn2+, but a lower affinity for Mg2+ and Ca2+. TPEN induces DNA damage and increases intracellular ROS production. TPEN also inhibits cell proliferation and induces apoptosis.
    TPEN
  • HY-13594
    Chlorin e6
    		99.51%
    Chlorin e6 is a photosensitizer and has strong absorption peaks at wavelength of 402 and 662 nm, as well as exhibiting intense fluorescence at 668 nm. Chlorin e6 has antimicrobial efficacy and anticancer activity. Chlorin e6 induces cell apoptosis via caspase-3 activation and can be used for the research of cancer.
    Chlorin e6
  • HY-B0143
    Niacin
    		99.96%
    Niacin (Vitamin B3) is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Niacin (Vitamin B3) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin (Vitamin B3) is also used in the study of cardiovascular diseases.
    Niacin
  • HY-116677
    Tris(benzyltriazolylmethyl)amine
    		99.88%
    Tris(benzyltriazolylmethyl)amine (TBTA) is a ligand that acts as a biochemical tool for the tagging of proteins and enzymes.
    Tris(benzyltriazolylmethyl)amine
  • HY-D0837
    Imidazole
    		99.96%
    Imidazole (Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene) is a heterocyclic aromatic compound. Imidazole bearing molecules have been used as corrosion, acetylcholinesterase (AChEI) and xanthine oxidase (XO) inhibitors, performing biological activities such as antifungal, antituberculosis, anti-inflammatory, antioxidant, and analgesic, amongst many others. Imidazole inhibits the enzymatic conversion of the endoperoxides (PGG2 and PGH2) to thromboxane A2 by platelet microsomes. Imidazole derivatives exhibits inhibition on SARS-CoV-2 3CLPro enzyme, which is promising for research in the field of Alzheimer’s disease, gout, COVID-19 and thrombo-embolic disease.
    Imidazole
  • HY-W074644
    1,3,6,8-Tetrakis[p-benzoic acid]pyrene
    		99.35%
    1,3,6,8-Tetrakis[p-benzoic acid]pyrene (4,4',4'',4'''-(Pyrene-1,3,6,8-tetrayl)tetrabenzoic acid) is a metal-organic framework (MOF).
    1,3,6,8-Tetrakis[p-benzoic acid]pyrene
  • HY-W004588
    tBu2bpy
    		99.39%
    tBu2bpy is a ligand of [Ru(tBu2bpy)2(phox)]PF6, which together contributes to anticancer activity, showing and LC50 values of 1.3 and 0.3 μM in HeLa cells after 24- and 72-hour incubation, respectively[1[.
    tBu2bpy
  • HY-Y0689
    Thiocarbonyldiimidazole
    		99.74%
    Thiocarbonyldiimidazole is a metal-organic framework (MOF).
    Thiocarbonyldiimidazole
  • HY-100807
    Quinolinic acid
    		99.97%
    Quinolinic acid, an endogenous metabolite of tryptophan, is a N-methyl-D-aspartate receptor (NMDA receptor) agonist. Quinolinic acid increases glutamate efflux, induces the generation of ROS, activates nitric oxide synthase, produces excessive NO, leading to calcium ion influx and neuronal apoptosis.
    Quinolinic acid
  • HY-D0020
    2,2'-Bipyridine
    		99.95%
    2,2'-Bipyridine is the unique molecular scaffold of the bioactive natural products. 2,2'-Bipyridine is extensively used as the core structure of many chelating ligands by acting as a bridge in the arrangement of the catalytic center. 2,2'-Bipyridine shows robust redox stability and hyperglycemic activity.
    2,2'-Bipyridine
  • HY-79880
    N,N'-Carbonyldiimidazole
    		99.9%
    N,N'-Carbonyldiimidazole (1,1'-Carbonyldiimidazole) is a highly reactive carboxylating reagent that can activate hydroxyl groups to form reactive carbonyl groups. N,N'-Carbonyldiimidazole can be used as a coupling agent and a peptide synthesis reagent.
    N,N'-Carbonyldiimidazole
  • HY-D0034
    9,10-Anthracenediyl-bis(methylene)dimalonic acid
    		98.00%
    9,10-Anthracenediyl-bis(methylene)dimalonic acid (ABMDMA) is a biological dye and indicator used to detect singlet oxygen generation (SOG). 9,10-Anthracenediyl-bis(methylene)dimalonic acid is water-soluble derivative of anthracene. 9,10-Anthracenediyl-bis(methylene)dimalonic acid can be photobleached by singlet oxygen to its corresponding endoperoxide. This reaction can be monitored spectrophotometrically by recording the decrease of absorbance at 400 nm.
    9,10-Anthracenediyl-bis(methylene)dimalonic acid
  • HY-101398
    Coproporphyrin III
    		99.57%
    Coproporphyrin III (Zincphyrin) is a naturally occurring porphyrin derivative that is mainly found in urine.
    Coproporphyrin III
  • HY-I0660
    Picolinic acid
    		99.98%
    Picolinic acid (PCL 016) is a topical antiviral agent, which inhibits adenovirus replication in rabbits.
    Picolinic acid
  • HY-15930
    TMB
    		99.98%
    TMB is a non-toxic, non-mutagenic, colorless dye that is also used as a chromogenic agent in enzyme detection systems based on horseradish peroxidase (HRP). TMB can function as a photoacoustic probe for reactive oxygen and nitrogen species (ROS/RNS), reacting with hypochlorite, hydrogen peroxide, singlet oxygen, and nitrogen dioxide to produce blue oxidation products. TMB can detect the singlet oxygen produced by the outer membrane of Escherichia coli ATCC 25922.
    TMB
  • HY-N2581
    Phytic acid sodium salt
    Phytic acid (myo-Inositol; hexakis dihydrogen phosphate; Inositol hexaphosphate) sodium salt is an orally active compound. Phytic acid sodium salt can be derived from the seeds of legumes. Phytic acid sodium salt is a [PO4]3- storage depot and precursor for other inositol phosphates and pyrophosphates. Phytic acid sodium salt attenuates Aβ oligomers and upregulates autophagy protein. Phytic acid sodium salt can be used in cardiovascular disease, metabolic disease, nervous system disease and cancer research.
    Phytic acid sodium salt
  • HY-W010184
    4,6-Dioxoheptanoic acid
    		98.81%
    4,6-Dioxoheptanoic acid is a potent inhibitor of heme biosynthesis.
    4,6-Dioxoheptanoic acid
  • HY-W008852
    Tetrakis (4-carboxyphenyl) porphyrin
    		98.86%
    Tetrakis (4-carboxyphenyl) porphyrin (TCPP) plays the role of a metal remover.
    Tetrakis (4-carboxyphenyl) porphyrin
  • HY-W075517
    ZIF-8
    ZIF-8 (2-Methylimidazole zinc salt) is a pyroptosis inducer that activates the caspase-1/gasdermin D-dependent pyroptosis pathway. ZIF-8 induces pyroptotic cell death accompanied by necrosis and immunogenic cell death. ZIF-8 initiates in situ immunity, activates anti-tumor immunity, and reprograms the immunosuppressive tumor microenvironment to inhibit tumor growth. ZIF-8 acts as a pH-responsive and stimulus-responsive drug release inducer. ZIF-8 is applicable to cancer-related research.
    ZIF-8
  • HY-103656
    Tetraphenylporphyrin
    		99.43%
    Tetraphenylporphyrin (TPP) is a symmetrically substituted porphyrin-based heterocyclic compound and used as a structural block for supramolecular synthesis. Tetraphenylporphyrin derivatives can be used for cancer research.
    Tetraphenylporphyrin