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Imidazole (Synonyms: 1,3-Diaza-2,4-cyclopentadiene; Glyoxaline)

Cat. No.: HY-D0837 Purity: 99.75%
Handling Instructions

Imidazole is a planar 5-membered ring.

For research use only. We do not sell to patients.

Imidazole Chemical Structure

Imidazole Chemical Structure

CAS No. : 288-32-4

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10 mM * 1 mL in Water USD 55 In-stock
Estimated Time of Arrival: December 31
500 mg USD 50 In-stock
Estimated Time of Arrival: December 31
5 g USD 60 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Publications Citing Use of MCE Imidazole

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Description

Imidazole is a planar 5-membered ring. Imidazole is a highly polar compound. Imidazole has been used extensively as a corrosion inhibitor. Imidazole is incorporated into many important biological molecules. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Imidazole is useful as a buffer in the pH range of 6.2-7.8 One of the applications of imidazole is in the purification of His-tagged proteins in immobilised metal affinity chromatography(IMAC). Imidazole is used to elute tagged proteins bound to Ni ions attached to the surface of beads in the chromatography column. An excess of imidazole is passed through the column, which displaces the His-tag from nickel co-ordination, freeing the His-tagged proteins. Imidazole has become an important part of many pharmaceuticals. Synthetic imidazoles are present in many fungicides and antifungal, antiprotozoal, and antihypertensive medications. Imidazole is part of the theophylline molecule, found in tea leaves and coffee beans, which stimulates the central nervous system. It is present in the anticancer medication mercaptopurine, which combats leukemia by interfering with DNA activities.

Molecular Weight

68.08

Formula

C₃H₄N₂

CAS No.

288-32-4

SMILES

C1=NC=CN1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL (1468.86 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 14.6886 mL 73.4430 mL 146.8860 mL
5 mM 2.9377 mL 14.6886 mL 29.3772 mL
10 mM 1.4689 mL 7.3443 mL 14.6886 mL
*Please refer to the solubility information to select the appropriate solvent.
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Product name:
Imidazole
Cat. No.:
HY-D0837
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