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Cat. No.: HY-D0837R

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Imidazole (Standard)

(Synonyms: Glyoxaline (Standard); 1,3-Diaza-2,4-cyclopentadiene (Standard))

1 Cited Publications

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Based on 1 publication(s) in Google Scholar

Imidazole (Standard) is the analytical standard of Imidazole. This product is intended for research and analytical applications. Imidazole (Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene) is a heterocyclic aromatic compound. Imidazole bearing molecules have been used as corrosion, acetylcholinesterase (AChEI) and xanthine oxidase (XO) inhibitors, performing biological activities such as antifungal, antituberculosis, anti-inflammatory, antioxidant, and analgesic, amongst many others. Imidazole inhibits the enzymatic conversion of the endoperoxides (PGG2 and PGH2) to thromboxane A2 by platelet microsomes. Imidazole derivatives exhibits inhibition on SARS-CoV-2 3CLPro enzyme, which is promising for research in the field of Alzheimer’s disease, gout, COVID-19 and thrombo-embolic disease.

For research use only. We do not sell to patients.

CAS No.: 288-32-4
Formula: C₃H₄N₂
Molecular Weight:68.08

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Please store the product under the recommended conditions in the Certificate of Analysis.

Imidazole (Standard) Chemical Structure

CAS No.: 288-32-4

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Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 288-32-4
Molecular Weight 68.08
Formula C₃H₄N₂
SMILES

C1=NC=CN1
Synonyms

Glyoxaline (Standard); 1,3-Diaza-2,4-cyclopentadiene (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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EMBO Mol Med

Isoginkgetin antagonizes ALS pathologies in its animal and patient iPSC models via PINK1-Parkin-dependent mitophagy. [Abstract]

2025 Oct 15. PMID: 41094045

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Noriega-Iribe E, et al. In vitro and in silico screening of 2, 4, 5-trisubstituted imidazole derivatives as potential xanthine oxidase and acetylcholinesterase inhibitors, antioxidant, and antiproliferative agents[J]. Applied Sciences, 2020, 10(8): 2889.

[2]. Ashish M. Kanhed, et al. Design and synthesis of diphenyl-1H-imidazole analogs targeting Mpro/3CLpro enzyme of SARS-CoV-2. Medicinal Chemistry Research, 2024 June 26, 1554-8120.

[3]. Moncada S, et al. Imidazole: a selective inhibitor of thromboxane synthetase[J]. Prostaglandins. 1977 Apr;13(4):611-8. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Imidazole (Standard)

1 Cited Publications

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Imidazole (Standard)

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