1. Screening Libraries
  2. Ferroptosis Compound Library

Ferroptosis Compound Library

Cat. No.: HY-L051
Library Contents: XLSX PDF SDF

Ferroptosis is a novel type of cell death program that is distinct from apoptosis, necroptosis and autophagy. It is dependent on iron and reactive oxygen species (ROS) and is characterized by lipid peroxidation. As a novel type of cell death, ferroptosis has distinct properties and recognizing functions involved in physical conditions or various diseases including cancers, neurodegenerative diseases, acute renal failure, etc.

A unique collection of 427 ferroptosis signal pathway related compounds with ferroptosis-inducing or -inhibitory activity. A useful tool to study ferroptosis mechanism as well as related diseases.

MCE Ferroptosis Compound Library can be supplied as pre-dissolved Solutions or Solid. For pre-dissolved solutions in this library, there are 420 compounds supplied in 10 mM solution and 7 compounds supplied in 2 mM solution.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, and 2 mM for compounds with solubility between 2 mM and 10 mM.

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
Size (Pre-dissolved Solution or Solid) Price Stock
30 μL/well Solution

10 mM and 2 mM
Pre-dissolved Solution

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50 μL/well Solution

10 mM and 2 mM
Pre-dissolved Solution

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100 μL/well Solution

10 mM and 2 mM
Pre-dissolved Solution

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2 × 100 μL/well Solution

10 mM and 2 mM
Pre-dissolved Solution

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  • Description

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Description
& Advantages

•   A unique collection of 427 bioactive ferroptosis signal pathway related compounds for high throughput screening (HTS) and high content screening (HCS).

•   Targets include glutathione peroxidase 4, iron, dipeptidylpeptidase 4, lipoxygenase, p53, etc.

•   A useful tool for the research of the regulation of ferroptosis and related diseases.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some compounds have been approved by FDA.

•   Structurally diverse, medicinally active, and cell permeable.

•   More detailed compound information with structure, IC50, and brief introduction.

•   NMR and HPLC validated to ensure high purity and quality.

•   All compounds are in stock and continuously updated.

Product Details
Formulation:
A collection of 427 ferroptosis compounds supplied as pre-dissolved Solutions or Solid
Solution: 420 compounds supplied in 10 mM solution, 7 compounds supplied in 2 mM solution.
Container:
96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Storage:
-80°C
Shipping:
Blue ice
Composition

Ferroptosis Compound Library

Source: MedChem Express

Documentation

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    Cat. No.:
    HY-L051
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    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack