TNF Superfamily Ligands

About 19 tumour necrosis factor (TNF) superfamily (TNFSF) ligands are currently identified, which include TNF-α, TNF-β, lymphotoxin-β (LT-β), CD27L, CD30L, CD40L, FasL, 4-1BBL, OX40L, TRAIL (TNF-related apoptosis-inducing ligand), LIGHT (homologous to lymphotoxins), RANKL (receptor activator of NF-κB ligand), TWEAK (TNF-related weak inducer of apoptosis), APRIL (a proliferation-inducing ligand), BAFF (B-cell activating factor), VEGI (vascular endothelial cell-growth inhibitor), ectodysplasin A (