1. Recombinant Proteins
  2. Cytokines and Growth Factors CD Antigens
  3. TNF Superfamily
  4. TNF Superfamily Ligands
  5. TRAIL/Apo2L Protein, Human

TRAIL/Apo2L Protein, Human

Cat. No.: HY-P7306
Handling Instructions

TRAIL/Apo2L Protein, Human is a protein functioning as a ligand that induces the process of apoptosis through engagement of death receptors.

For research use only. We do not sell to patients.

Protein Expression Service

Recombinant Proteins-MedChemExpress
Size Price Stock Quantity
10 μg $80 In-stock
Estimated Time of Arrival: December 31
50 μg $180 In-stock
Estimated Time of Arrival: December 31
100 μg   Get quote  
250 μg   Get quote  

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Publications Citing Use of MCE TRAIL/Apo2L Protein, Human

TRAIL/Apo2L Protein, Human Related Classifications

  • Technical Parameters

  • Properties

  • Documentation

Species

Human

Source

E. coli

Tag

Tag Free

Accession

P50591 (V114-G281)

Gene ID

8743

Synonyms
rHuTRAIL/Apo2L; TNFSF10; CD253
AA Sequence

MVRERGPQRVAAHITGTRGRSNTLSSPNSKNEKALGRKINSWESSRSGHSFLSNLHLRNGELVIHEKGFYYIYSQTYFRFQEEIKENTKNDKQMVQYIYKYTSYPDPILLMKSARNSCWSKDAEYGLYSIYQGGIFELKENDRIFVSVTNEHLIDMDHEASFFGAFLVG

Molecular Weight

Approximately 20 kDa

Biological Activity
The ED50 is <40 ng/mL as measured by RPMI-8226 cells, corresponding to a specific activity of >2.5 × 104 units/mg.
Appearance

Lyophilized powder.

Formulation

Lyophilized after extensive dialysis against PBS.

Endotoxin Level

<0.2 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O or PBS.

Storage & Stability

Stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Background

Apo2L/TRAIL is one of several members of the TNF gene superfamily that induce apoptosis through engagement of death receptors[1]. TRAIL and its receptors have been used as the targets of several anti-cancer therapeutic. TRAIL has also been implicated as a pathogenic or protective factor in various pulmonary diseases, particularly pulmonary arterial hypertension[2].

Documentation
References
  • Reconstitution Calculator

  • Dilution Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
TRAIL/Apo2L Protein, Human
Cat. No.:
HY-P7306
Quantity:
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