Cystatin A
Cystatin A, or stefin A, is a type 1 cystatin: a small, non-glycosylated inhibitor that resides in the cytosol rather than being secreted. It is abundant in keratinocytes and other squamous epithelia, where it is incorporated into the cornified cell envelope during terminal differentiation and inhibits cathepsins B, H, and L to protect tissue from uncontrolled proteolysis. Cystatin A levels rise in psoriatic epidermis, and its expression is reduced in several carcinomas, consistent with a protective, differentiation-linked role. Recombinant cystatin A is used in cysteine-protease inhibition studies and in research on epidermal barrier formation.
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Cystatin A Recombinant Proteins (1)
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
