2. Isotope-Labeled Compounds
  3. Isotope-Labeled Bile Acids

Isotope-Labeled Bile Acids

Bile Acids ( BAs ) are the main organic component of bile, which is the general name of several similar steroid acids. BAs are generally classified into primary bile acids and secondary bile acids according to the source. They can also be divided into free bile acids and conjugated bile acids according to the chemical structure. MedChemExpress ( MCE ) offers a wide variety of Stable Isotope-Labeled Bile Acids that can be used as internal standards for the quantitative GC/LC-MS analysis and involved the study of bile acid synthesis, transport, and metabolism etc.

Isotope-Labeled Bile Acids (61):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0324S
    Cholic acid-d4 116380-66-6 99.91%
    Cholic acid-d4 is the deuterium labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.
    Cholic acid-d<sub>4</sub>
  • HY-76847S
    Chenodeoxycholic Acid-d4 99102-69-9 99.94%
    Chenodeoxycholic Acid-d4 is the deuterium labeled Chenodeoxycholic Acid. Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism.
    Chenodeoxycholic Acid-d<sub>4</sub>
  • HY-N0593S
    Deoxycholic acid-d4 112076-61-6 99.80%
    Deoxycholic acid-d4 is the deuterium labeled Deoxycholic acid. Deoxycholic acid is specifically responsible for activating the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.
    Deoxycholic acid-d<sub>4</sub>
  • HY-N1423S
    Glycocholic acid-d4 1201918-15-1 99.92%
    Glycocholic acid-d4 is the deuterium labeled Glycocholic acid (HY-N1423). Glycocholic acid is a bile acid derivative. Glycocholic acid downregulates MDR1, Bcl-2, MRP1, MRP2 and FXR, upregulates Bax, p53, caspase-9, caspase-3, TGR5 and S1PR2. Glycocholic acid inhibits multidrug resistance and efflux pumps, induces mitochondrial apoptosis, and enhances chemosensitivity. Glycocholic acid modulates related bile acid receptor signaling. Glycocholic acid suppresses growth and conjugation of Enterobacteriaceae and increases their antibiotic susceptibility. Glycocholic acid can be used for the research of colon adenocarcinoma and cholangiocarcinoma (CCA).
    Glycocholic acid-d<sub>4</sub>
  • HY-B1788S
    Taurocholic acid-d4 sodium 2410279-93-3 ≥99.0%
    Taurocholic acid-d4 (sodium) is the deuterium labeled Taurocholic acid. Taurocholic acid (N-Choloyltaurine) is a bile acid involved in the emulsification of fats.
    Taurocholic acid-d<sub>4</sub> sodium
  • HY-N2334S
    Glycochenodeoxycholic acid-d4 1201918-16-2 99.95%
    Glycochenodeoxycholic acid-d4 is the deuterium labeled Glycochenodeoxycholic acid. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) induces hepatocyte apoptosis.
    Glycochenodeoxycholic acid-d<sub>4</sub>
  • HY-B0172S
    Lithocholic acid-d4 83701-16-0 99.91%
    Lithocholic acid-d4 is the deuterium labeled Lithocholic acid, which is a toxic secondary bile acid.
    Lithocholic acid-d<sub>4</sub>
  • HY-N0324S1
    Cholic acid-d5 53007-09-3 99.80%
    Cholic acid-d5 is the deuterium labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.
    Cholic acid-d<sub>5</sub>
  • HY-113478S
    Ursodeoxycholic acid-d4 347841-46-7 99.52%
    Ursodeoxycholic acid-2,2,4,4-d4 is the deuterium labeled Ursodeoxycholic acid (HY-13771). Ursodeoxycholic acid is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5, GPCR19) and the farnesoid X receptor (FXR). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Ursodeoxycholic acid also reduces ACE2 expression and is beneficial for reducing SARS-CoV-2 infection.
    Ursodeoxycholic acid-d<sub>4</sub>
  • HY-N0324S2
    Cholic acid-13C 52886-36-9 99.17%
    Cholic acid-13C is the 13C-labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.
    Cholic acid-<sup>13</sup>C
  • HY-125731S
    Glycodeoxycholic acid-d4 1069132-37-1 99.90%
    Glycodeoxycholic acid-d4 is the deuterium labeled Glycodeoxycholic Acid. Glycodeoxycholic Acid is an endogenous metabolite.
    Glycodeoxycholic acid-d<sub>4</sub>
  • HY-N1424S
    Glycoursodeoxycholic acid-d4 2044276-17-5 99.78%
    Glycoursodeoxycholic acid-d4 (Ursodeoxycholylglycine-d4) is the deuterium labeled Glycoursodeoxycholic acid. Glycoursodeoxycholic acid, a acyl glycine and a bile acid-glycine conjugate, is a metabolite of ursodeoxycholic acid.
    Glycoursodeoxycholic acid-d<sub>4</sub>
  • HY-N2027S
    Taurochenodeoxycholic acid-d4 sodium 2410279-85-3 99.20%
    Taurochenodeoxycholic acid-d4 (sodium) is the deuterium labeled Taurochenodeoxycholic acid. Taurochenodeoxycholic acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid induces apoptosis and shows obvious anti-inflammatory and immune regulation properties.
    Taurochenodeoxycholic acid-d<sub>4</sub> sodium
  • HY-76847S3
    Chenodeoxycholic acid-d5 52840-12-7 99.79%
    Chenodeoxycholic acid-d5 is the deuterium labeled Chenodeoxycholic Acid. Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism.
    Chenodeoxycholic acid-d<sub>5</sub>
  • HY-N0593S3
    Deoxycholic acid-13C 52886-37-0 98.0%
    Deoxycholic acid-13C is the 13C-labeled Deoxycholic acid. Deoxycholic acid is specifically responsible for activating the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.
    Deoxycholic acid-<sup>13</sup>C
  • HY-B1788S1
    Taurocholic acid-d4 252030-90-3 99.50%
    Taurocholic acid-d4 is deuterium labeled Taurocholic acid. Taurocholic acid (N-Choloyltaurine) is a bile acid involved in the emulsification of fats.
    Taurocholic acid-d<sub>4</sub>
  • HY-116374S
    Glycolithocholic acid-d4 2044276-16-4 99.37%
    Glycolithocholic acid-d4 is the deuterium labeled Glycolithocholic acid. Glycolithocholic acid, an endogenous metabolite, is a glycine-conjugated secondary bile acid and can be used to diagnose ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH) and primary sclerosing cholangitis (PSC) .
    Glycolithocholic acid-d<sub>4</sub>
  • HY-N1429S1
    Taurochenodeoxycholic acid-d5 sodium 98.12%
    Taurochenodeoxycholic acid-d5 (sodium) is the deuterium labeled Taurochenodeoxycholic acid sodium. Taurochenodeoxycholic acid sodium salt (12-Deoxycholyltaurine sodium salt) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid induces apoptosis and shows obvious anti-inflammatory and immune regulation properties.
    Taurochenodeoxycholic acid-d<sub>5</sub> sodium
  • HY-N0593S1
    Deoxycholic acid-d5 52840-14-9 99.90%
    Deoxycholic acid-d5 is the deuterium labeled Deoxycholic acid. Deoxycholic acid is specifically responsible for activating the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.
    Deoxycholic acid-d<sub>5</sub>
  • HY-76847S2
    Chenodeoxycholic acid-13C 52918-92-0 98.0%
    Chenodeoxycholic acid-13C is the 13C-labeled Chenodeoxycholic Acid. Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism.
    Chenodeoxycholic acid-<sup>13</sup>C