1. Signaling Pathways
  2. GPCR/G Protein
  3. Adiponectin Receptor

Adiponectin Receptor

Adiponectin is a protein which in humans is encoded by the ADIPOQ gene. It is involved in regulating glucose levels as well as fatty acid breakdown. The hormone plays a role in the suppression of the metabolic derangements that may result intype 2 diabetes, obesity, atherosclerosis, non-alcoholic fatty liver disease and an independent risk factor for metabolic syndrome. Adiponectin binds to a number of receptors. Two receptors have been identified with homology to G protein-coupled receptors, and one receptor similar to the cadherin family: adiponectin receptor 1 and adiponectin receptor 2.

Adiponectin Receptor Related Products (3):

Cat. No. Product Name Effect Purity
  • HY-15848
    AdipoRon Agonist 99.76%
    AdipoRon is an orally active adiponectin receptor (AdipoR) agonist, binding to AdipoR1 and AdipoR2 with Kds of 1.8 and 3.1 μM, respectively.
  • HY-N0166
    Gramine Agonist 99.45%
    Gramine (Donaxine) is a natural alkaloid isolated from giant reed, acts as an active adiponectin receptor (AdipoR) agonist, with IC50s of 3.2 and 4.2 µM for AdipoR2 and AdipoR1, respectively. Gramine is also a human and mouse β2-Adrenergic receptor (β2-AR) agonist. Gramine (Donaxine) has anti-tumor, anti-viral and anti-inflammatory properties.
  • HY-110164
    AdipoRon hydrochloride Agonist
    AdipoRon hydrochloride is an orally active and specific AdipoR agonist, binding to AdipoR1 and AdipoR2, with Kds of 1.8 and 3.1 μM, respectively.
Isoform Specific Products

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