CD29/Integrin beta-1
Integrin beta 1, the CD29 antigen, is the beta subunit shared by the beta1 integrin family that pairs with at least twelve alpha chains, including CD49a-f, to form receptors for collagen, laminin and fibronectin. The chain is broadly expressed on leukocytes, endothelial and epithelial cells and hematopoietic progenitors, where it anchors cells to extracellular matrix and transduces survival, migration and differentiation signals through focal adhesion kinase and associated adaptors. In the immune system, CD29 contributes to lymphocyte homing, T-cell costimulation and macrophage adhesion. It also marks mesenchymal stromal cells, and its dysregulation promotes tumor invasion and fibrotic remodeling.
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CD29/Integrin beta-1 Recombinant Proteins (2)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
