맞춤형 펩타이드 합성

Peptides are compounds formed by amino acids linked through peptide bonds. They exhibit diverse biological functions and are often used in functional analysis, antibody research, and especially in the field of drug research and development.

MedChemExpress (MCE) provides a full spectrum of high-quality custom peptide services including fast peptide synthesis, standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant polypeptide expression. We are fully capable of meeting the ever-increasing peptide needs in biological and drug discovery research.

  • Advantages

  • General Workflow

  • Online Quotation

  • Related Services

  • FAQ

Advantages

Comprehensive Products
linear peptides, cyclic peptides, conjugated peptides, labeled peptides, peptide libraries.
Flexible Quantities
from mg to kg.
Comprehensive Modifications
more than 300 modifications ranging from phosphorylation, disulfide bridges, special amino acids, fluorescent labeling and conjugations.
Guaranteed Quality
standard QC report including HPLC, MS and COA. We can also provide additional analyses upon your requirements.
Professional Technical Support
MedChemExpress (MCE) technical account managers and online resources to support our customers from the beginning to the end of their peptide-based research.

General Workflow

  • Starting with sequence and structure information
  • Get your quotation within 1~2 working days
  • Peptide synthesis
  • Product purification
  • Standard quality control
  • Delivery

Online Quotation

Application Information

  • MCE Japan Authorized Agent:

Batch Upload

Excel Template Download

Upload My Order

Online Form

Please fill out our online form in accordance with the following instruction. Please specify any other special requirements in the remarks.
1. The minimum quantity is 1 mg. Please specify an integer amount of ≥1 mg.
2. Input amino acid sequences from N-terminal to C-terminal. Both single-letter and three-letter amino acid codes are accepted.
3. Uppercase letters in the single-letter code denote the L-configuration, while lowercase letters denote the D-configuration by default. For D-amino acids in three-letter code, please use {d-Glu} as a reference.
4. Solubility test only includes solvents below: H2O, DMSO, PBS, Normal saline solution.
5. If not specifically selected, the default formulation will be lyophilized powder with 95% purity in TFA salt form.

Peptide name CAS No. * Sequence (N'-C') N-terminal modifications C-terminal modifications Other modifications Disulfide bridges * Requested quantity Aliquot Purity Salt form Solubility test Additional analyses Remarks Operate
Example Amylin, amide, human 122384-88-7 KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY -NH2 Cys2-Cys7 5mg 1mg*5 95% TFA DMSO
1

Note：

1. The custom order form can be submitted via the official website or by email ([email protected]). Fields marked with * are required.
2. Peptide customization orders include HPLC, MS, and COA reports by default. If additional quality analyses are required, please specify them in the form.
3. There is a risk of failure in custom product synthesis. If your experiment requires multiple custom products and you cannot accept any synthesis failure within one order, please indicate this in the remarks.
4. If you do not receive a reply within 1–3 business days after submitting, please contact us by phone or email for confirmation. Do not place duplicate orders. Customers will be responsible for any costs incurred due to duplicate submissions

Related Services

Peptide-drug conjugates (PDCs)
A PDC consists of three components: one or more cytotoxin, a linker and a targeting peptide. It possesses the advantages of peptides including small molecular weight, biodegradability, and low immunogenicity. The hydrophobicity and ionization properties can be adjusted by modifications and sequence alterations, therefore addressing solubility and metabolism problems.
MCE provides custom synthesis services for PDCs and related products. You can click here to download PDC quotation files and submit it by email ([email protected]) .
Radionuclide-drug conjugates (RDCs)
A RDC is consisting of a targeting unit, a linker, a chelator and a radioactive nuclide. A targeting vector formed by conjugating targeting peptide with chelator can be further labeled with a radioactive nuclide, enabling targeted radiotherapy or imaging.
MCE provides custom synthesis services for targeting peptides and peptide–chelator conjugates. Please specify the required chelator in the custom peptide synthesis form.
Peptide-Phosphorodiamidate Morpholino Oligomer conjugates (PPMOs)
PPMOs are functional molecules formed by coupling cell-penetrating peptides (CPPs) with PMOs. It combines the high specificity of PMOs with the delivery advantages of peptides, resulting in potential applications in gene therapy and nucleic acid drug development.
MCE provides custom synthesis services for PPMOs and related products. Please specify the required sequence and structure in according quotations
DSPE-PEG peptide conjugates
DSPE-PEG peptide conjugates combine functional peptides with amphiphilic lipid-polymer hybrid structure. They integrate the self-assembly properties of lipids with the membrane-targeting capability of peptides, enabling the formation of nanomicelles, liposomes or other carrier structures in aqueous solutions. They exhibit potential applications in drug delivery and molecular imaging.
MCE provides custom synthesis services for DSPE-PEG peptide conjugate and related products. Please specify the required sequence and structure in according quotations.
Peptide Nucleic Acids (PNAs)
PNAs are synthetic analogs of nucleic acids in which the canonical sugar–phosphate backbone is substituted with a neutral, peptide-like structure. By integrating the sequence programmability of nucleic acids with the structural stability of a peptide backbone, PNAs exhibit high biocompatibility and hold significant promise for a wide range of biomedical applications.
MCE provides custom synthesis services for PNAs and related products. Please specify the required sequence and structure in according quotations.

FAQ

1. What about the amino acid abbreviations and general physicochemical properties?

You may refer to our Amino Acid Reference Chart first. For special amino acids, please use the full name or include their chemical information in the remarks section if necessary.

2. What types of peptide modifications can MCE provide?

Please refer to the modification list for details.

3. How to dissolve peptides?

(1) Please refer to the product’s solubility testing results. If the report is not available, please contact us.

(2) You can also refer to our peptide solubility guidelines for details.

4. What kind of data reports are provided for custom peptides?

The default analysis report includes HPLC, MS and COA.

5. What kinds of additional analyses can MCE provide?

Elemental analysis, heavy metal testing, moisture determination, NMR and various other quality analyses can be provided for custom peptides. In addition to HPLC and MS analysis, please specify the analyses in according quotations if needed. Kindly contact us for any further questions.

6. What are the differences between various peptide salt forms, and how should they be selected?

Common peptide salt forms include TFA salt, acetate salt, ammonium salt, hydrochloride salt, sodium salt and citrate salt. In general, salt formation does not affect the biological activity of peptides. TFA salt may theoretically exhibit some level of cytotoxicity, therefore its concentration should be considered when conducting cell-based or animal experiments. Acetate salt has minimal biological toxicity, leading to the preferred choice for biological studies. Whether desalted products are available depends on the specific peptide structure and desalting may affect peptide solubility.

By default, custom peptides are provided in TFA salt form. According to customers’ feedback, the influence of TFA in actual experiments is minimal. If desalting or salt exchange is required, please specify this in your quotation.

7. How to restore peptides?

It is recommended to store peptides at -20 °C or -80 °C. Fluorescent-labeled peptides should be kept away from light. Please avoid repeated freezing and thawing. You can refer to our peptide storge guidelines for details.