MSR1/CD204
MSR1, known as CD204 or macrophage scavenger receptor class A, is a trimeric receptor built from collagen-like and scavenger receptor cysteine-rich domains. It binds a broad array of polyanionic ligands, most prominently acetylated and oxidized low-density lipoprotein, and mediates their internalization without the cholesterol-mediated feedback regulation that constrains foam cell formation. The receptor is expressed on macrophages and dendritic cell subsets and also contributes to host defense by binding bacterial endotoxins and lipoteichoic acid. MSR1 participates in lipid deposition during atherogenesis, and polymorphisms in the gene have been associated with Alzheimer disease susceptibility, keeping the receptor relevant to both cardiovascular and neurodegeneration research.
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MSR1/CD204 Recombinant Proteins (4)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formel: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
