Angiotensin-converting Enzyme (ACE)

Related Products

Angiotensin-converting enzyme (ACE) indirectly increases blood pressure by causing blood vessels to constrict. ACE does that by converting angiotensin I to angiotensin II, which constricts the vessels. ACE, angiotensin I and angiotensin II are part of the renin-angiotensin system (RAS), which controls blood pressure by regulating the volume of fluids in the body. ACE is secreted in the lungs and kidneys by cells in the endothelium (inner layer) of blood vessels. It has two primary functions: ACE catalyses the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor in a substrate concentration-dependent manner. ACE degrades bradykinin, a potent vasodilator, and other vasoactive peptides. These two actions make ACE inhibition a goal in the treatment of conditions such as high blood pressure, heart failure, diabetic nephropathy, and type 2 diabetes mellitus. Inhibition of ACE (by ACE inhibitors) results in the decreased formation of angiotensin II and decreased metabolism of bradykinin, leading to systematic dilation of the arteries and veins and a decrease in arterial blood pressure.

Angiotensin-converting Enzyme (ACE) Related Products (34):

By Effects:	Inhibitors (34)

Cat. No.	Product Name	Effect	Purity

HY-12403

Angiotensin 1-7 Inhibitor 99.61%

Angiotensin (1-7) inhibits purified canine angiotensin converting enzyme (ACE) activity with an IC₅₀ of 0.65 μM.
HY-B0368

Captopril Inhibitor 98.05%

Captopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE).
HY-B0331A

Enalapril maleate Inhibitor 99.96%

Enalapril Maleate, the active metabolite of enalapril, is an angiotensin-converting enzyme (ACE) inhibitor.
HY-B0093A

Benazepril hydrochloride Inhibitor 99.85%

Benazepril hydrochloride, an angiotensin converting enzyme inhibitor, which is a medication used to treat high blood pressure.
HY-18206A

Lisinopril dihydrate Inhibitor >98.0%

Lisinopril Dihydrate is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks.

Angiotensin 1-7	Inhibitor	99.61%
Angiotensin (1-7) inhibits purified canine angiotensin converting enzyme (ACE) activity with an IC₅₀ of 0.65 μM.

Captopril	Inhibitor	98.05%
Captopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE).

Enalapril maleate	Inhibitor	99.96%
Enalapril Maleate, the active metabolite of enalapril, is an angiotensin-converting enzyme (ACE) inhibitor.

Benazepril hydrochloride	Inhibitor	99.85%
Benazepril hydrochloride, an angiotensin converting enzyme inhibitor, which is a medication used to treat high blood pressure.

Lisinopril dihydrate	Inhibitor	>98.0%
Lisinopril Dihydrate is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks.

HY-109592

Imidaprilate	Inhibitor
Imidaprilate is an active metabolite of TA-6366, acts as a potent angiotensin converting enzyme (ACE) inhibitor, with an IC₅₀ of 2.6 nM, and is used in the research of hypertensive disease.

HY-N2021A

Phosphoramidon Disodium	Inhibitor	>98.0%
Phosphoramidon disodium is a metalloprotease inhibitor. Phosphoramidon inhibits endothelin-converting enzyme (ECE), neutral endopeptidase (NEP), and angiotensin-converting enzyme (ACE) with IC₅₀ values of 3.5, 0.034, and 78 μM, respectively.

HY-B0592

Trandolapril Inhibitor 98.01%

Trandolapril(RU44570) is an ACE inhibitor used to treat high blood pressure.
HY-B0130A

Perindopril erbumine Inhibitor 99.90%

Perindopril erbumine is a potent ACE inhibitor of which is used to treat high blood pressure, heart failure or stable coronary artery disease.
HY-B0279

Ramipril Inhibitor 99.81%

Ramipril is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 5 nM.

Trandolapril	Inhibitor	98.01%
Trandolapril(RU44570) is an ACE inhibitor used to treat high blood pressure.

Perindopril erbumine	Inhibitor	99.90%
Perindopril erbumine is a potent ACE inhibitor of which is used to treat high blood pressure, heart failure or stable coronary artery disease.

Ramipril	Inhibitor	99.81%
Ramipril is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 5 nM.

HY-B0382

Fosinopril sodium	Inhibitor	>98.0%
Fosinopril Sodium is the ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension and some types of chronic heart failure.

HY-B0477

Quinapril hydrochloride Inhibitor 99.10%

Quinapril is a prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications.
HY-18208

Omapatrilat Inhibitor

Omapatrilat is a dual inhibitor of the metalloproteases ACE and NEP with K_i values of 0.64 and 0.45 nM, respectively.
HY-B0384

Temocapril hydrochloride Inhibitor 99.52%

Temocapril Hydrochloride is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension.
HY-B0231

Enalaprilat dihydrate Inhibitor >99.0%

Enalaprilat is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 1.94 nM.
HY-A0043A

Cilazapril monohydrate Inhibitor 98.63%

Cilazapril Monohydrate is a angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure.

Quinapril hydrochloride	Inhibitor	99.10%
Quinapril is a prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications.

Omapatrilat	Inhibitor
Omapatrilat is a dual inhibitor of the metalloproteases ACE and NEP with K_i values of 0.64 and 0.45 nM, respectively.

Temocapril hydrochloride	Inhibitor	99.52%
Temocapril Hydrochloride is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension.

Enalaprilat dihydrate	Inhibitor	>99.0%
Enalaprilat is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 1.94 nM.

Cilazapril monohydrate	Inhibitor	98.63%
Cilazapril Monohydrate is a angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure.

HY-P0318

Hemorphin-7	Inhibitor	99.65%
Hemorphin-7 is a hemorphin peptide, an endogenous opioid peptide derived from the β-chain of hemoglobin. Hemorphin peptides exhibits antinociceptive and antihypertensive activities, activating opioid receptors and inhibiting angiotensin-converting enzyme (ACE). Sequence: Tyr-Pro-Trp-Thr-Gln-Arg-Phe.

HY-B0130

Perindopril Inhibitor

Perindopril is a long-acting ACE inhibitor of which is used to treat high blood pressure, heart failure or stable coronary artery disease.
HY-B0655

Zofenopril calcium Inhibitor

Zofenopril Calcium(SQ26991) is an antioxidant that acts as an angiotensin-converting enzyme inhibitor.

Perindopril	Inhibitor
Perindopril is a long-acting ACE inhibitor of which is used to treat high blood pressure, heart failure or stable coronary artery disease.

Zofenopril calcium	Inhibitor
Zofenopril Calcium(SQ26991) is an antioxidant that acts as an angiotensin-converting enzyme inhibitor.

HY-B0378A

Moexipril hydrochloride	Inhibitor	98.49%
Moexipril HCl is a potent orally active non-sulfhydryl angiotensin converting enzyme(ACE) inhibitor, which is used for the treatment of hypertension and congestive heart failure.

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