Angiotensin-converting Enzyme (ACE)

Related Products

Angiotensin-converting enzyme (ACE) indirectly increases blood pressure by causing blood vessels to constrict. ACE does that by converting angiotensin I to angiotensin II, which constricts the vessels. ACE, angiotensin I and angiotensin II are part of the renin-angiotensin system (RAS), which controls blood pressure by regulating the volume of fluids in the body. ACE is secreted in the lungs and kidneys by cells in the endothelium (inner layer) of blood vessels. It has two primary functions: ACE catalyses the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor in a substrate concentration-dependent manner. ACE degrades bradykinin, a potent vasodilator, and other vasoactive peptides. These two actions make ACE inhibition a goal in the treatment of conditions such as high blood pressure, heart failure, diabetic nephropathy, and type 2 diabetes mellitus. Inhibition of ACE (by ACE inhibitors) results in the decreased formation of angiotensin II and decreased metabolism of bradykinin, leading to systematic dilation of the arteries and veins and a decrease in arterial blood pressure.

Angiotensin-converting Enzyme (ACE) Related Products (39):

By Effects:	Inhibitors (38)

Cat. No.	Product Name	Effect	Purity

HY-12403

Angiotensin 1-7 Inhibitor 99.61%

Angiotensin (1-7) inhibits purified canine angiotensin converting enzyme (ACE) activity with an IC₅₀ of 0.65 μM.
HY-B0368

Captopril Inhibitor 98.05%

Captopril (SQ-14534) is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE).
HY-B0093A

Benazepril hydrochloride Inhibitor 99.85%

Benazepril hydrochloride, an angiotensin converting enzyme inhibitor, which is a medication used to treat high blood pressure.
HY-B0331A

Enalapril maleate Inhibitor 99.96%

Enalapril (maleate) (MK-421 (maleate)), the active metabolite of enalapril, is an angiotensin-converting enzyme (ACE) inhibitor.

Angiotensin 1-7	Inhibitor	99.61%
Angiotensin (1-7) inhibits purified canine angiotensin converting enzyme (ACE) activity with an IC₅₀ of 0.65 μM.

Captopril	Inhibitor	98.05%
Captopril (SQ-14534) is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE).

Benazepril hydrochloride	Inhibitor	99.85%
Benazepril hydrochloride, an angiotensin converting enzyme inhibitor, which is a medication used to treat high blood pressure.

Enalapril maleate	Inhibitor	99.96%
Enalapril (maleate) (MK-421 (maleate)), the active metabolite of enalapril, is an angiotensin-converting enzyme (ACE) inhibitor.

HY-N2021A

Phosphoramidon Disodium	Inhibitor	>98.0%
Phosphoramidon disodium is a metalloprotease inhibitor. Phosphoramidon inhibits endothelin-converting enzyme (ECE), neutral endopeptidase (NEP), and angiotensin-converting enzyme (ACE) with IC₅₀ values of 3.5, 0.034, and 78 μM, respectively.

HY-W009732

Sinapinic acid	Inhibitor	99.61%
Sinapinic acid (Sinapic acid) is a phenolic compound isolated from Hydnophytum formicarum Jack. Rhizome, acts as an inhibitor of HDAC, with an IC₅₀ of 2.27 mM, and also inhibits ACE-I activity. Sinapinic acid posssess potent anti-tumor activity, induces apoptosis of tumor cells. Sinapinic acid shows antioxidant and antidiabetic activities. Sinapinic acid reduces total cholesterol, triglyceride, and HOMA-IR index, and also normalizes some serum parameters of antioxidative abilities and oxidative damage in ovariectomized rats.

HY-106446

Rentiapril Inhibitor

Rentiapril is an orally active angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity.
HY-114424

H-Ile-Pro-Pro-OH Inhibitor

H-Ile-Pro-Pro-OH, a milk-derived peptide, inhibits angiotensin-converting enzyme (ACE) with an IC₅₀ of 5 μM. Antihypertensive tripeptides.
HY-B0130A

Perindopril erbumine Inhibitor 99.33%

Perindopril erbumine is a potent ACE inhibitor of which is used to treat high blood pressure, heart failure or stable coronary artery disease.

Rentiapril	Inhibitor
Rentiapril is an orally active angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity.

H-Ile-Pro-Pro-OH	Inhibitor
H-Ile-Pro-Pro-OH, a milk-derived peptide, inhibits angiotensin-converting enzyme (ACE) with an IC₅₀ of 5 μM. Antihypertensive tripeptides.

Perindopril erbumine	Inhibitor	99.33%
Perindopril erbumine is a potent ACE inhibitor of which is used to treat high blood pressure, heart failure or stable coronary artery disease.

HY-B0382

Fosinopril sodium	Inhibitor	>98.0%
Fosinopril Sodium is the ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension and some types of chronic heart failure.

HY-18206A

Lisinopril dihydrate Inhibitor >98.0%

Lisinopril Dihydrate is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks.
HY-B0592

Trandolapril Inhibitor 98.01%

Trandolapril(RU44570) is an ACE inhibitor used to treat high blood pressure.
HY-B0279

Ramipril Inhibitor 99.81%

Ramipril (HOE-498) is an angiotensin-converting enzyme (ACE) inhibitor with IC₅₀ of 5 nM.
HY-B0384

Temocapril hydrochloride Inhibitor 99.52%

Temocapril Hydrochloride is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension.
HY-B0231

Enalaprilat dihydrate Inhibitor >99.0%

Enalaprilat (dihydrate) (MK-422) is an angiotensin-converting enzyme (ACE) inhibitor with IC₅₀ of 1.94 nM.
HY-B0477

Quinapril hydrochloride Inhibitor 99.10%

Quinapril (hydrochloride) (CI-906) is a prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications.
HY-18208

Omapatrilat Inhibitor

Omapatrilat is a dual inhibitor of the metalloproteases ACE and NEP with K_i values of 0.64 and 0.45 nM, respectively.
HY-B1451

Imidapril hydrochloride Inhibitor 99.95%

Imidapril Hydrochloride is the hydrochloride salt of Imidapril, an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
HY-A0043A

Cilazapril monohydrate Inhibitor 98.63%

Cilazapril Monohydrate is a angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure.

Lisinopril dihydrate	Inhibitor	>98.0%
Lisinopril Dihydrate is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks.

Trandolapril	Inhibitor	98.01%
Trandolapril(RU44570) is an ACE inhibitor used to treat high blood pressure.

Ramipril	Inhibitor	99.81%
Ramipril (HOE-498) is an angiotensin-converting enzyme (ACE) inhibitor with IC₅₀ of 5 nM.

Temocapril hydrochloride	Inhibitor	99.52%
Temocapril Hydrochloride is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension.

Enalaprilat dihydrate	Inhibitor	>99.0%
Enalaprilat (dihydrate) (MK-422) is an angiotensin-converting enzyme (ACE) inhibitor with IC₅₀ of 1.94 nM.

Quinapril hydrochloride	Inhibitor	99.10%
Quinapril (hydrochloride) (CI-906) is a prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications.

Omapatrilat	Inhibitor
Omapatrilat is a dual inhibitor of the metalloproteases ACE and NEP with K_i values of 0.64 and 0.45 nM, respectively.

Imidapril hydrochloride	Inhibitor	99.95%
Imidapril Hydrochloride is the hydrochloride salt of Imidapril, an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.

Cilazapril monohydrate	Inhibitor	98.63%
Cilazapril Monohydrate is a angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure.

HY-P0318

Hemorphin-7	Inhibitor	99.65%
Hemorphin-7 is a hemorphin peptide, an endogenous opioid peptide derived from the β-chain of hemoglobin. Hemorphin peptides exhibits antinociceptive and antihypertensive activities, activating opioid receptors and inhibiting angiotensin-converting enzyme (ACE).

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