1. Metabolic Enzyme/Protease
    Apoptosis
  2. Angiotensin-converting Enzyme (ACE)
    Apoptosis
  3. Perindopril erbumine

Perindopril erbumine (Synonyms: Perindopril tert-butylamine salt; S-9490 erbumine)

Cat. No.: HY-B0130A Purity: 99.83%
Handling Instructions

Perindopril erbumine (Perindopril tert-butylamine salt) is a potent ACE inhibitor of which is used to treat high blood pressure, heart failure or stable coronary artery disease.

For research use only. We do not sell to patients.

Perindopril erbumine Chemical Structure

Perindopril erbumine Chemical Structure

CAS No. : 107133-36-8

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10 mM * 1 mL in DMSO USD 79 In-stock
Estimated Time of Arrival: December 31
100 mg USD 72 In-stock
Estimated Time of Arrival: December 31
500 mg USD 216 In-stock
Estimated Time of Arrival: December 31
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Description

Perindopril erbumine (Perindopril tert-butylamine salt) is a potent ACE inhibitor of which is used to treat high blood pressure, heart failure or stable coronary artery disease. Target: ACE Perindopril is a long-acting ACE inhibitor. It is used to treat high blood pressure, heart failure or stable coronary artery disease in form of perindopril arginine (trade names include Coversyl, Coversum) or perindopril erbumine (trade name Aceon). According to the Australian government's Pharmaceutical Benefits Scheme website, based on data provided to the Australian Department of Health and Aging by the manufacturer, perindopril arginine and perindopril erbumine are therapeutically equivalent and may be interchanged without differences in clinical effect. However the dose prescribed to achieve the same effect will differ due to different molecular weights for the two forms. Perindopril is one of the most prescribed inhibitors of angiotensin converting enzyme, has a large evidence base, which allows to use it in patients with hypertension, diabetes mellitus type 2, coronary heart disease and chronic heart failure. In this review, the author focused on the evidence of organoprotecting properties of perindopril that lie outside lowering blood pressure.

Clinical Trial
Molecular Weight

441.60

Formula

C₂₃H₄₃N₃O₅

CAS No.

107133-36-8

SMILES

O=C([[email protected]]1N(C([[email protected]@H](N[[email protected]](C(OCC)=O)CCC)C)=O)[[email protected]@]2([H])CCCC[[email protected]@]2([H])C1)O.CC(C)(C)N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : ≥ 50 mg/mL (113.22 mM)

DMSO : 10 mg/mL (22.64 mM; Need ultrasonic)

*"≥" means soluble, but saturation unknown.

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Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2645 mL 11.3225 mL 22.6449 mL
5 mM 0.4529 mL 2.2645 mL 4.5290 mL
10 mM 0.2264 mL 1.1322 mL 2.2645 mL
*Please refer to the solubility information to select the appropriate solvent.
References

Purity: 99.83%

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Keywords:

PerindoprilPerindopril tert-butylamineS-9490S9490S 9490Angiotensin-converting Enzyme (ACE)ApoptosisInhibitorinhibitorinhibit

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Perindopril erbumine
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