Astrocytoma
Gliomas are among the most frequent and aggressive primary tumors of the central nervous system (CNS) in adults. The nomenclature of gliomas depends on the glial cell of origin. Astrocytomas and glioblastomas (GBMs) refer to gliomas of astrocytic origin, oligodendrogliomas of oligodendrocytes and ependymomas of ependymal cells, respectively. Astrocytomas and, in particular, their most severe form, glioblastoma, are the most aggressive primary brain tumors.
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Astrocytoma (2)
Basiliximab
Synonyms: CHI 621
- Molecular Weight: 143.56 kDa
Basiliximab (CHI 621) is a recombinant chimeric murine/human IgG1 monoclonal anti-interleukin-2 receptor antibody. Basiliximab can be used for the research of renal transplantation.
P2Y2R antagonist-2
Cat. No.: HY-189243
- Formula: C26H24ClN7O5S
- Molecular Weight: 582.03
P2Y2R antagonist-2 is an antagonist of the P2Y2 receptor (P2Y2R), with a pKi value of 6.53 for human P2Y2R. P2Y2R antagonist-2 blocks UTPγS (HY-137603)-induced calcium mobilization, binds to the orthosteric site of P2Y2R to displace fluorescent antagonist ligands, and forms unique binding interactions. P2Y2R antagonist-2 has no structural alerts, exhibiting low lipophilicity and high lipophilic efficiency. P2Y2R antagonist-2 can be used in studies related to astrocytoma and inflammation.
