2. Immunology/Inflammation
  3. Interleukin Related
  4. Basiliximab

Basiliximab  (Synonyms: CHI 621)

Cat. No.: HY-108852 Purity: 95.0%
COA

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Basiliximab (CHI 621) is a recombinant chimeric murine/human IgG1 monoclonal anti-interleukin-2 receptor antibody. Basiliximab can be used for the research of renal transplantation.

For research use only. We do not sell to patients.

Basiliximab Chemical Structure

Basiliximab Chemical Structure

CAS No. : 179045-86-4

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Basiliximab Related Antibodies

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Description

Basiliximab (CHI 621) is a recombinant chimeric murine/human IgG1 monoclonal anti-interleukin-2 receptor antibody. Basiliximab can be used for the research of renal transplantation[1].

IC50 & Target

Interleukin-2 receptor[1]
In Vitro

Basiliximab specifically inhibits T lymphocyte proliferation by binding to the IL-2Rα[1].
Basiliximab binds only to activated lymphocytes and macrophages/monocytes[3].
Basiliximab does not affect resting T lymphocytes that do not express IL-2Rα[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Basiliximab Related Antibodies
In Vivo

Basiliximab (CHI 621) (0.07 mg/rat; i.v.; once) decreases total placental natural killer cells in reduced uterine perfusion pressure (RUPP) rats[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Timed-pregnant Sprague Dawley (SD) rats, reduced uterine perfusion pressure (RUPP) rat model of placental ischemia[2]
Dosage: 0.07 mg/rat
Administration: IV infusion, once
Result: Decreased total placental natural killer cells. Had no effect to lower MAP or improve pup weight and placental weight.
Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Basiliximab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation

Purity: 95.0%

COA (231 KB)

Handling Instructions (2659 KB)
References
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Basiliximab Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Basiliximab179045-86-4CHI 621CHI621CHI-621Interleukin RelatedILrenal transplantationplacental ischemiapreeclampsiaInhibitorinhibitorinhibit

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