2. Signaling Pathways
  3. Immunology/Inflammation
  4. Interleukin Related
  5. IL-1 Isoform

IL-1

 
Cat. No. Product Name Effect Purity
  • HY-B0240
    Disulfiram
    		Inhibitor 99.78%
    Disulfiram (Tetraethylthiuram disulfide) is a specific inhibitor of aldehyde-dehydrogenase (ALDH1), used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol.
  • HY-108841
    Raleukin
    		Antagonist 99.40%
    Raleukin (AMG-719) is a recombinant, nonglycosylated human interleukin-1 receptor (IL-1R) antagonist.
  • HY-B1081A
    Oxidopamine hydrobromide
    		Inducer 99.95%
    Oxidopamine (6-OHDA) hydrobromide is an antagonist of the neurotransmitter dopamine.
  • HY-B1081
    Oxidopamine hydrochloride
    		Inducer 99.91%
    Oxidopamine (6-OHDA) hydrochloride is an antagonist of the neurotransmitter dopamine.
  • HY-N0633
    Muscone
    		Inhibitor ≥98.0%
    Muscone is the main active monomer of traditional Chinese medicine musk.
  • HY-P99235
    Nadunolimab
    		Inhibitor 98.11%
    Nadunolimab is a human monoclonal IgG1 antibody targeting IL1RAP.
  • HY-108822
    Rilonacept
    		Inhibitor
    Rilonacept (Arcalyst), a dimeric fusion protein, is a interleukin 1 inhibitor.
  • HY-P99379
    Nidanilimab
    		Inhibitor
    Nidanilimab (CAN04) is a fully humanized monoclonal anti-IL1RAP antibody with a Kd value of 1.10 pM.
  • HY-N0283
    Diacerein
    		Inhibitor 98.78%
    Diacerein (Diacerhein), a interleukin-1 beta inhibitor, is a slow-acting medicine of the class anthraquinone used to treat joint diseases.
  • HY-15509A
    Semapimod tetrahydrochloride
    		Inhibitor 98.43%
    Semapimod tetrahydrochloride (CNI-1493), an inhibitor of proinflammatory cytokine production, can inhibit TNF-α, IL-1β, and IL-6.
  • HY-N0619
    Mulberroside A
    		Inhibitor 99.75%
    Mulberroside A is one of the main bioactive constituent in mulberry (Morus alba L.
  • HY-N0569
    Madecassic acid
    		Inhibitor 99.23%
    Madecassic acid is isolated from Centella asiatica (Umbelliferae).
  • HY-N0042
    Ginsenoside Rc
    		Inhibitor ≥98.0%
    Ginsenoside Rc, one of major Ginsenosides from Panax ginseng, enhances GABA receptorA (GABAA)-mediated ion channel currents (IGABA).
  • HY-N0722
    Neochlorogenic acid
    		Inhibitor 99.07%
    Neochlorogenic acid is a natural polyphenolic compound found in dried fruits and other plants.
  • HY-P1110
    AF12198
    		Inhibitor 99.75%
    AF12198 is a potent, selective and specific peptide antagonist for human type I interleukin-1 receptor (IL1-R1) (IC50=8 nM) but not the human type II receptor (IC50=6.7 µM) or the murine type I receptor (IC50>200 µM).
  • HY-N0604
    Ginsenoside Rh1
    		Inhibitor ≥98.0%
    Ginsenoside Rh1 (Prosapogenin A2) inhibits the expression of PPAR-γ, TNF-α, IL-6, and IL-1β.
  • HY-15507
    VGX-1027
    		Inhibitor 99.76%
    VGX-1027 is an orally active isoxazole compound that exhibits various immunomodulatory properties.
  • HY-N7176
    Kaempferol 3-O-β-D-glucuronide
    		Inhibitor 99.41%
    Kaempferol 3-O-β-D-glucuronide (Kaempferol-3-glucuronide), one conjugated kaempferol metabolite, has anti-inflammatory effect.
  • HY-130252
    YQ128
    		Inhibitor 99.83%
    YQ128 is a potent and selective second-generation NLRP3 (NOD-like receptor P3) inflammasome inhibitor with an IC50 of 0.30 µM.
  • HY-101860
    GIBH-130
    		Inhibitor 99.95%
    GIBH-130 is an effective inhibitor of neuroinflammation.
Cat. No. Product Name / Synonyms Species Source