1. Inhibitory Antibodies
  2. Anakinra

Anakinra (Synonyms: Raleukin; AMG-719)

Cat. No.: HY-108841
Handling Instructions

Anakinra (Raleukin) is a recombinant, nonglycosylated human interleukin-1 receptor (IL-1R) antagonist. Anakinra is the first biological agent to block the pro-inflammatory effects.

For research use only. We do not sell to patients.

Anakinra Chemical Structure

Anakinra Chemical Structure

CAS No. : 143090-92-0

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10 mg USD 550 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1650 In-stock
Estimated Time of Arrival: December 31
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Description

Anakinra (Raleukin) is a recombinant, nonglycosylated human interleukin-1 receptor (IL-1R) antagonist. Anakinra is the first biological agent to block the pro-inflammatory effects[1][2].

IC50 & Target

IL-1R[1].

In Vivo

Combined etanercept (5 mg/kg, ip) and Anakinra (100 mg/kg, I.P. daily for 7 days) substantially improves marginal mass human islet engraftment in immunodeficient mice[2].
Anakinra enhances tumor growth inhibition in mice receiving peptide vaccination and β-(1-3),(1-6)-D-glucan[3].

Clinical Trial
Molecular Weight

17257.60

Formula

C₇₅₉H₁₁₈₆N₂₀₈O₂₃₂S₁₀

CAS No.

143090-92-0

SMILES

[Anakinra]

Storage

Store at 4°C, Do not freeze

References
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Keywords:

AnakinraRaleukinAMG-719AMG719AMG 719OthersrheumatoidarthritisInhibitorinhibitorinhibit

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