1. Screening Libraries
  2. FDA-Approved Drug Library Plus

FDA-Approved Drug Library Plus

Cat. No.: HY-L022P
Library Contents: XLSX PDF SDF

New drug development is a time-consuming and high-cost process. Drug repurposing (also called drug repositioning, reprofiling or re‑tasking) offers various advantages over developing an entirely new drug for a given indication. First, the risk of failure is lower. Second, the time frame for drug development can be reduced. Third, less investment is needed. Approved drugs have identified bioactivities, good pharmacokinetic characteristics and safety which are suitable for drug repurposing.

MCE owns a unique collection of 2497 marketed compounds which have been completed extensive preclinical and clinical studies and have well-characterized bioactivities, safety and bioavailability properties. MCE FDA-Approved Drug Library Plus, with more powerful screening capability, further complements FDA-Approved Drug Library (HY-L022) by adding some compounds with low solubility or solution stability (Part B) to this library. All those supplementary are supplied in powder form.

MCE FDA-Approved Drug Library Plus can be supplied as pre-dissolved Solutions or Solid. For pre-dissolved solutions in this library, there are 2279 compounds supplied in 10 mM solution, 37 compounds supplied in 2 mM solution and 16 compounds supplied in 3 mg/mL solution.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

  • 96-well Plate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
Size (Pre-dissolved Solution or Solid) Price Stock
30 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

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50 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

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100 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

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2 × 100 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

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  • Description

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Description
& Advantages

•   A unique collection of 2497 marketed drugs for high throughput screening (HTS) and high content screening (HCS).

•   Used in the research of oncology, cardiology, anti-inflammatory, immunology, dermatology, endocrinology, neurology, and more.

•   A useful tool for researching new targets of marketed old drugs.

•   All compounds have been approved by the FDA or EMA.

•   Structurally diverse, bioactive, and cell permeable.

•   More detailed compound information with structure, IC50, and brief introduction.

•   NMR and HPLC validated ensure high purity.

•   All compounds are in stock and continuously updated.

Product Details
Formulation:
A collection of 2497 marketed drugs supplied as pre-dissolved Solutions or Solid
Solution: 2279 compounds supplied in 10 mM solution, 37 compounds supplied in 2 mM solution, 16 compounds supplied in 3 mg/mL solution.
Container:
96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Storage:
-80°C
Shipping:
Blue ice
Composition

FDA-Approved Drug Library Plus

Source: MedChem Express

Documentation

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    Product Name:
    FDA-Approved Drug Library Plus
    Cat. No.:
    HY-L022P
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    • 96-well Plate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack