Etrolizumab (rhuMAb Beta7) is a Gut-selective, Anti-β7 Integrin McAb for Inflammatory Bowel Disease (IBD) Research2022-11-05Etrolizumab (rhuMAb Beta7) is a gut-selective, anti-β7 integrin monoclonal antibody. Etrolizumab decreases β7 integrins of T lymphocytes. Etrolizumab can be used for the research of inflammatory bowel disease.
2022-08-20Pelecopan is a potent, selective, and orally active complement factor D inhibitor, possessing the potential to study paroxysmal nocturnal hemoglobinuria (PNH).
2022-03-28BM213 is a selective C5aR1 agonist. It’s a useful research tool to study C5aR1 function
2022-01-28CL097 is a TLR7/8 agonist. CL097 induces pro-nflammatory cytokines. CL097 induces NADPH oxidase priming and efficient diabetogenic cytotoxic T lymphocyte (CTL) function in NOD mice.
2021-07-14EMD527040 is a highly selective αvβ6 antagonist with antifibrotic activities.
2021-05-27Butaprost is a selective prostaglandin E receptor (EP2) agonist. Butaprost can effectively mitigate kidney fibrogenesis in various fibrosis models.
2021-03-10CC-90001 is a potent, selective, and orally active inhibitor of JNK. CC-90001 can be used for the research of idiopathic pulmonary fibrosis (IPF).
2020-10-14Giredestrant (GDC-9545) is an orally active and selective estrogen receptor (ER) antagonist. Giredestrant has highly potent in vivo efficacy with anti-tumor activity.
Molnupiravir (EIDD-2801) is an Orally Active Antiviral Compound Against COVID-19 and Influenza Virus2020-04-18Molnupiravir is a potent broad-spectrum antiviral agent. Molnupiravir shows antiviral effects against SARS-CoV in vivo by oral administration. Molnupiravir has the potential for COVID-19, and seasonal and pandemic influenza treatment.
2019-11-17Adagrasib (MRTX849) is an orally active and covalent inhibitor of KRASG12C. Adagrasib effects KRASG12C modification, inhibits KRAS inhibition and shows anti-tumor efficacy.
- November 2022 (1)
- August 2022 (1)
- March 2022 (1)
- January 2022 (1)
- July 2021 (1)
- May 2021 (1)
- March 2021 (1)
- October 2022 (1)
- April 2020 (1)
- November 2019 (1)
- August 2019 (2)
- June 2019 (2)
- April 2019 (3)