1. GPCR/G Protein
    Neuronal Signaling
  2. Neurokinin Receptor

Neurokinin Receptor

Neurokinin Receptor Related Products (12):

Cat. No. Product Name Effect Purity
  • HY-10052
    Aprepitant Inhibitor 99.32%
    Aprepitant is an antiemetic chemical compound that belongs to a class of drugs called substance P antagonists (SPA). It mediates its effect by blocking the neurokinin 1 (NK1) receptor.
  • HY-10053
    Maropitant Antagonist 99.64%
    Maropitant is a neurokinin (NK1) receptor antagonist.
  • HY-14552
    Talnetant Antagonist 99.7%
    Talnetant (SB 223412) is a potent and selective NK3 receptor antagonist(ki=1.4 nM, hNK-3-CHO); 100-fold selective for the hNK-3 versus hNK-2 receptor, with no affinity for the hNK-1 at concentrations up to 100 uM.
  • HY-16346
    Netupitant Antagonist 99.47%
    Netupitant(CID-6451149) is a highly potent and selective, orally active neurokinin-1 receptor antagonist with Ki of 0.95 nM.
  • HY-15722
    SB-222200 Antagonist 99.36%
    SB 222200 is a selective, reversible and competitive antagonist of human NK-3 receptor(Ki=4.4 nM) that effectively crosses the blood-brain barrier.
  • HY-14751
    Rolapitant Antagonist
    Rolapitant (SCH619734) is a potent, selective and orally active neurokinin NK1 receptor antagonist with a Ki of 0.66 nM.
  • HY-14407A
    Fosaprepitant dimeglumine Antagonist 99.06%
    Fosaprepitant dimeglumine(MK-0517) is a neurokinin-1 receptor antagonist for the prevention of chemotherapy-induced nausea and vomiting.
  • HY-16346S
    Netupitant D6 Antagonist >98.0%
    Netupitant D6 is the deuterium labeled Netupitant(CID-6451149), which is a highly potent and selective, orally active neurokinin-1 receptor antagonist.
  • HY-18006
    NKP608 Antagonist
    NKP608 is a non-peptidic derivative of 4-aminopiperidine which acts as a selective, specific and potent antagonist at the neurokinin-1 (NK-1) receptor both in vitro(IC50=2.6 nM) and in vivo.
  • HY-G0012S
    Monohydroxy Netupitant D6 Agonist
    Monohydroxy Netupitant D6 is the deuterium labeled Monohydroxy Netupitant, which is a metabolite of Netupitant.
  • HY-14407
    Fosaprepitant Antagonist
    Fosaprepitant (L-758298) is a neurokinin-1 receptor antagonist for the prevention of chemotherapy-induced nausea and vomiting.
  • HY-14552A
    Talnetant hydrochloride Antagonist
    Talnetant Hcl(SB 223412 Hcl) is a potent and selective NK3 receptor antagonist(ki=1.4 nM, hNK-3-CHO); 100-fold selective for the hNK-3 versus hNK-2 receptor, with no affinity for the hNK-1 at concentrations up to 100 uM.