2. Signaling Pathways
  3. Immunology/Inflammation
  4. Interleukin Related
  5. IL-4 Isoform

IL-4

 
Cat. No. Product Name Effect Purity
  • HY-14644
    Apilimod
    		Inhibitor 99.55%
    Apilimod (STA 5326) is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively.
  • HY-P9926
    Dupilumab
    		Inhibitor ≥99.2%
    Dupilumab (REGN-668) is a fully human mAb to IL-4 receptor α (IL-4Rα) that inhibits both IL-4 and IL-13 signaling, markedly improved moderate-to-severe atopic dermatitis.
  • HY-14644A
    Apilimod mesylate
    		Inhibitor 99.83%
    Apilimod (STA 5326) mesylate is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively.
  • HY-B0446
    Naphazoline hydrochloride
    		Inhibitor 98.37%
    Naphazoline (Naphthazoline) hydrochloride is a potent α-adrenergic receptor agonist.
  • HY-17002
    Suplatast (Tosilate)
    		Inhibitor 98.33%
    Suplatast Tosilate (IPD 1151T) is an orally active Th2 cytokine inhibitor which can inhibit both IL-4 and IL-5 production from Th2 cells and suppress IgE synthesis.
  • HY-P99238
    Rolinsatamab
    		Inhibitor
    Rolinsatamab is a potent dual IL-4 and IL-13 inhibitor as a fully humanized bispecific monoclonal antibody.
  • HY-108013
    Armillarisin A
    		99.89%
    Armillarisin A has the potential for the ulcerative colitis (UC) study.
  • HY-N0600
    Ginsenoside F3
    		Modulator 99.84%
    Ginsenoside F3, a component of PPTGs (an minor saponin in the leaves of Panax ginseng), has immunoenhancing activity by regulating production and gene expression of type 1 cytokines (IL-2, IFN-gamma) and type 2 cytokines (IL-4 and IL-10).
  • HY-111326A
    Naphazoline nitrate
    		Inhibitor
    Naphazoline (Naphthazoline) nitrate is an α-adrenergic receptor agonist.
  • HY-144684
    PDE4-IN-8
    		Inhibitor
    PDE4-IN-8 (Example 5) is a potent PDE4 inhibitor with an IC50 of 0.93 nM for PDE4B2.
  • HY-111326
    Naphazoline
    		Inhibitor
    Naphazoline (Naphthazoline) is a potent α-adrenergic receptor agonist.
Cat. No. Product Name / Synonyms Species Source