1. Signaling Pathways
  2. Immunology/Inflammation
  3. Interleukin Related
  4. IL-4 Isoform
  5. IL-4 Inhibitor

IL-4 Inhibitor

IL-4 Inhibitors (7):

Cat. No. Product Name Effect Purity
  • HY-P9926
    Dupilumab
    Inhibitor ≥99.2%
    Dupilumab (REGN-668) is a fully human mAb to IL-4 receptor α (IL-4Rα) that inhibits both IL-4 and IL-13 signaling, markedly improved moderate-to-severe atopic dermatitis.
  • HY-B0446
    Naphazoline hydrochloride
    Inhibitor 98.37%
    Naphazoline (Naphthazoline) hydrochloride is a potent α-adrenergic receptor agonist.
  • HY-17002
    Suplatast (Tosilate)
    Inhibitor 98.33%
    Suplatast Tosilate (IPD 1151T) is an orally active Th2 cytokine inhibitor which can inhibit both IL-4 and IL-5 production from Th2 cells and suppress IgE synthesis.
  • HY-P99238
    Rolinsatamab
    Inhibitor
    Rolinsatamab is a potent dual IL-4 and IL-13 inhibitor as a fully humanized bispecific monoclonal antibody.
  • HY-111326A
    Naphazoline nitrate
    Inhibitor
    Naphazoline (Naphthazoline) nitrate is an α-adrenergic receptor agonist.
  • HY-111326
    Naphazoline
    Inhibitor
    Naphazoline (Naphthazoline) is a potent α-adrenergic receptor agonist.
  • HY-144684
    PDE4-IN-8
    Inhibitor
    PDE4-IN-8 (Example 5) is a potent PDE4 inhibitor with an IC50 of 0.93 nM for PDE4B2.