1604678-82-1
1604678-82-1
Chemical Structure
PQA-18
- CAS No.: 1604678-82-1
- Formula:C25H31NO4
- Molecular Weight:409.52
SMILES: O=C(C1=NC2=C(OC/C=C(C)/C)C=CC=C2C(OC/C=C(C)/C)=C1)OC/C=C(C)\C
Biological Activity: PQA-18 is a unique PAK2 inhibitor (IC50: 10 nM). PQA-18 has immunosuppressing effects. PQA-18 suppresses IL2, IL4, IL6, and TNFα. PQA-18 inhibits the population of a subset of regulatory T cells and the immunoglobulin (Ig) production against T cell-dependent antigens as well as alleviates dermatitis in mice[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PQA-18 | 99.62% | PQA-18 is a unique PAK2 inhibitor (IC50: 10 nM). PQA-18 has immunosuppressing effects. PQA-18 suppresses IL2, IL4, IL6, and TNFα. PQA-18 inhibits the population of a subset of regulatory T cells and the immunoglobulin (Ig) production against T cell-dependent antigens as well as alleviates dermatitis in mice. | ||||||||||||||||||||
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References
Keywords
