1. Signaling Pathways
  2. Epigenetics
    JAK/STAT Signaling
    Stem Cell/Wnt
  3. JAK
  4. Tyk2 Inhibitors

Tyk2 Inhibitors

JAK1

JAK2

JAK3

Tyk2

JAK

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform Tyk2 together.

Please try each isoform separately.

Tyk2 Specific Inhibitors
Product Name Tyk2 JAK1 JAK2 JAK3 Tyk2 Selectivity Purity
Tyk2-IN-5
Tyk2 JH2, Ki: 0.086 nM
      Selective Inhibitor
Tyk2-IN-4
Tyk2
      Selective Inhibitor 99.76%
SAR-20347
Tyk2, IC50: 0.6 nM
JAK1, IC50: 23 nM
JAK2, IC50: 26 nM
JAK3, IC50: 41 nM
Selective Inhibitor 97.00%
TyK2-IN-2
Tyk2
      Selective Inhibitor 99.41%
Ruxolitinib
Tyk2, IC50: 19 nM
JAK1, IC50: 3.3 nM
JAK2, IC50: 2.8 nM
JAK3, IC50: 428 nM
Pan Inhibitor 99.99%
Baricitinib
Tyk2, IC50: 53 nM
JAK1, IC50: 5.9 nM
JAK2, IC50: 5.7 nM
JAK3, IC50: 560 nM
Pan Inhibitor 99.93%
Abrocitinib
Tyk2, IC50: 1253 nM
JAK1, IC50: 29 nM
JAK2, IC50: 803 nM
  Pan Inhibitor 99.79%
Filgotinib
Tyk2, IC50: 116 nM
JAK1, IC50: 10 nM
JAK2, IC50: 28 nM
JAK3, IC50: 810 nM
Pan Inhibitor 99.64%
Peficitinib
Tyk2, IC50: 4.8 nM
JAK1, IC50: 3.9 nM
JAK2, IC50: 5 nM
JAK3, IC50: 0.7 nM
Pan Inhibitor 99.43%
Gandotinib
Tyk2, IC50: 44 nM
 
JAK2, IC50: 3 nM
JAK3, IC50: 48 nM
Pan Inhibitor 99.96%
Delgocitinib
Tyk2, IC50: 58 nM
JAK1, IC50: 2.8 nM
JAK2, IC50: 2.6 nM
JAK3, IC50: 13 nM
Pan Inhibitor 99.14%
BMS-911543
Tyk2, IC50: 66 nM
JAK1, IC50: 75 nM
JAK2, IC50: 1.1 nM
JAK3, IC50: 360 nM
Pan Inhibitor 98.12%
Decernotinib
Tyk2, Ki: 11 nM
JAK1, Ki: 11 nM
JAK2, Ki: 13 nM
JAK3, Ki: 2.5 nM
Pan Inhibitor 98.91%
Oclacitinib maleate
Tyk2, IC50: 84 nM
JAK1, IC50: 10 nM
JAK2, IC50: 18 nM
JAK3, IC50: 99 nM
Pan Inhibitor 99.53%
Baricitinib phosphate
Tyk2, IC50: 53 nM
JAK1, IC50: 5.9 nM
JAK2, IC50: 5.7 nM
JAK3, IC50: 560 nM
Pan Inhibitor 99.49%
Ilginatinib
Tyk2, IC50: 22 nM
JAK1, IC50: 33 nM
JAK2, IC50: 0.72 nM
JAK3, IC50: 39 nM
Pan Inhibitor 95.88%
NVP-BSK805 dihydrochloride
TYK2 JH1, IC50: 10.76 nM
JAK1 JH1, IC50: 31.63 nM
JAK2 JH1, IC50: 0.48 nM
FL JAK2 V617F, IC50: 0.56 nM
FL JAK2 wt, IC50: 0.58 nM
JAK3 JH1, IC50: 18.68 nM
Pan Inhibitor 99.36%
GLPG0634 analog
Tyk2, IC50: <100 nM
   
JAK3, IC50: <100 nM
Pan Inhibitor 98.00%
Ilginatinib maleate
Tyk2, IC50: 22 nM
JAK1, IC50: 33 nM
JAK2, IC50: 0.72 nM
JAK3, IC50: 39 nM
Pan Inhibitor 97.04%
Ilginatinib hydrochloride
Tyk2, IC50: 22 nM
JAK1, IC50: 33 nM
JAK2, IC50: 0.72 nM
JAK3, IC50: 39 nM
Pan Inhibitor 98.02%
NVP-BSK805
TYK2 JH1, IC50: 10.76 nM
JAK1 JH1, IC50: 31.63 nM
JAK2 JH1, IC50: 0.48 nM
FL JAK2 V617F, IC50: 0.56 nM
FL JAK2 wt, IC50: 0.58 nM
JAK3 JH1, IC50: 18.68 nM
Pan Inhibitor
PF-06263276
Tyk2, IC50: 29.7 nM
JAK1, IC50: 2.2 nM
JAK2, IC50: 23.1 nM
JAK3, IC50: 59.9 nM
Pan Inhibitor
JAK-IN-3
Tyk2, IC50: 34 nM
JAK1, IC50: 5 nM
JAK2, IC50: 70 nM
JAK3, IC50: 3 nM
Pan Inhibitor
JAK/HDAC-IN-1
Tyk2, IC50: 49 nM
JAK1, IC50: 4.8 nM
JAK2, IC50: 4 nM
JAK3, IC50: 7.4 nM
Pan Inhibitor
BMS-066
Tyk2, IC50: 72 nM
      Pan Inhibitor
Ruxolitinib sulfate
Tyk2, IC50: 19 nM
JAK1, IC50: 3.3 nM
JAK2, IC50: 2.8 nM
JAK3, IC50: 428 nM
Pan Inhibitor