944118-01-8
944118-01-8
Chemical Structure
Peficitinib
Synonym(s): ASP015K; JNJ-54781532
- CAS No.: 944118-01-8
- Formula:C18H22N4O2
- Molecular Weight:326.39
IUPAC Name: 4-(((1R,2s,3S,5s,7s)-5-hydroxyadamantan-2-yl)amino)-1H-pyrrolo[2,3-b]pyridine-5-carboxamide
InChIKey: DREIJXJRTLTGJC-ZKVNVPQCSA-N
SMILES: O[C@](C[C@@H]1C[C@H]2C3)(C2)C[C@@H]3[C@H]1NC4=C5C(NC=C5)=NC=C4C(N)=O
Biological Activity: Peficitinib (ASP015K) is an orally active JAK inhibitor, with IC50s of 3.9, 5.0, 0.7 and 4.8 nM for JAK1, JAK2, JAK3 and Tyk2, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Peficitinib | 99.38% | Peficitinib (ASP015K) is an orally active JAK inhibitor, with IC50s of 3.9, 5.0, 0.7 and 4.8 nM for JAK1, JAK2, JAK3 and Tyk2, respectively. | ||||||||||||||||||||
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Peficitinib (Standard) | 99.53% | Peficitinib (Standard) is the analytical standard of Peficitinib. This product is intended for research and analytical applications. Peficitinib (ASP015K) is an orally active JAK inhibitor, with IC50s of 3.9, 5.0, 0.7 and 4.8 nM for JAK1, JAK2, JAK3 and Tyk2, respectively. | ||||||||||||||||||||
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Peficitinib-d3 | Peficitinib-d3 (ASP015K-d3) is the deuterium labeled Peficitinib (HY-19568). Peficitinib (ASP015K) is an orally active JAK inhibitor, with IC50s of 3.9, 5.0, 0.7 and 4.8 nM for JAK1, JAK2, JAK3 and Tyk2, respectively. | |||||||||||||||||||||
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References
