1263774-59-9
1263774-59-9
Chemical Structure
Delgocitinib
Synonym(s): JTE-052
- CAS No.: 1263774-59-9
- Formula:C16H18N6O
- Molecular Weight:310.35
IUPAC Name: 3-((3S,4R)-3-methyl-6-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1,6-diazaspiro[3.4]octan-1-yl)-3-oxopropanenitrile
InChIKey: LOWWYYZBZNSPDT-ZBEGNZNMSA-N
SMILES: O=C(N(C[C@@H]1C)[C@]21CN(C3=C(C=CN4)C4=NC=N3)CC2)CC#N
Biological Activity: Delgocitinib (JTE-052) is a specific JAK inhibitor with IC50s of 2.8, 2.6, 13 and 58 nM for JAK1, JAK2, JAK3 and Tyk2, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Delgocitinib | 99.61% | Delgocitinib (JTE-052) is a specific JAK inhibitor with IC50s of 2.8, 2.6, 13 and 58 nM for JAK1, JAK2, JAK3 and Tyk2, respectively. | ||||||||||||||||||||
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Delgocitinib (Standard) | ≥98% | Delgocitinib (Standard) is the analytical standard of Delgocitinib (HY-109053). This product is intended for research and analytical applications. Delgocitinib (JTE-052) is a specific JAK inhibitor with IC50s of 2.8, 2.6, 13 and 58 nM for JAK1, JAK2, JAK3 and Tyk2, respectively. | ||||||||||||||||||||
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References
Keywords
