1229236-86-5
1229236-86-5
Chemical Structure
Gandotinib
Synonym(s): LY2784544
- CAS No.: 1229236-86-5
- Formula:C23H25ClFN7O
- Molecular Weight:469.94
IUPAC Name: 3-(4-chloro-2-fluorobenzyl)-2-methyl-N-(3-methyl-1H-pyrazol-5-yl)-8-(morpholinomethyl)imidazo[1,2-b]pyridazin-6-amine
InChIKey: SQSZANZGUXWJEA-UHFFFAOYSA-N
SMILES: CC1=NNC(NC2=NN3C(C(CN4CCOCC4)=C2)=NC(C)=C3CC5=CC=C(C=C5F)Cl)=C1
Biological Activity: Gandotinib (LY2784544) is a potent JAK2 inhibitor with IC50 of 3 nM. Gandotinib (LY2784544) also inhibits FLT3, FLT4, FGFR2, TYK2, and TRKB with IC50 of 4, 25, 32, 44, and 95 nM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Gandotinib | 99.86% | Gandotinib (LY2784544) is a potent JAK2 inhibitor with IC50 of 3 nM. Gandotinib (LY2784544) also inhibits FLT3, FLT4, FGFR2, TYK2, and TRKB with IC50 of 4, 25, 32, 44, and 95 nM. | ||||||||||||||||||||
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Keywords
