FLT3-IN-31
FLT3-IN-31 (compound 10q) is a potent FLT3 inhibitor with IC50 values of 0.16, 2.4 nM for FLT3, FLT3-D835Y, resprctively. FLT3-IN-31 shows antiproliferation activity. FLT3-IN-31 decreases the protein expression of p-FLT3, P-STAT5, P-ERK. FLT3-IN-31 induces apoptosis and cell cycle arrest at G1 phase. FLT3-IN-31 shows antitumor activity.
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- No. CAS: 2290545-53-6
- Fòrmula: C25H24FN5O
- Peso molecular:429.49
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
Chemical Information
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No. CAS 2290545-53-6
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Peso molecular 429.49
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Fòrmula C25H24FN5O
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SMILES
NC1=NC=CC(C2=CC=C3C(NN=C3/C=C/C4=CC=C(C(F)=C4)CN5CCOCC5)=C2)=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)