Copy Link Print Information

Dupilumab

(Synonyms: REGN-668; SAR-231893)
6 Cited Publications
Customer Review

Based on 6 publication(s) in Google Scholar

Dupilumab (REGN-668) is a fully human mAb to IL-4 receptor α (IL-4Rα) that inhibits both IL-4 and IL-13 signaling, markedly improved moderate-to-severe atopic dermatitis.

For research use only. We do not sell to patients.

  • Purity: ≥99.2%
  • CAS No.: 1190264-60-8
  • Molecular Weight:147 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Dupilumab
  • Experimental Validation Results for Dupilumab
  • Experimental Validation Results for Dupilumab
  • Experimental Validation Results for Dupilumab
  • Experimental Validation Results for Dupilumab
  • Experimental Validation Results for Dupilumab
  • Experimental Validation Results for Dupilumab
  • Dupilumab Chemical Structure
    Dupilumab Chemical Structure
CAS No.: 1190264-60-8
Size
Price
Stock
Quantity
Amount: USD 0.00
Please select quantity
or
or

* Please select Quantity before adding items.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Chemical Information
  • Purity & Documentation
  • References
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products

Publications Citing Use of MedChemExpress (MCE) Dupilumab

More
Customer Validation & Images
ELISART-PCRCell Imaging/StainingFlow CytometryIF
  • ELISA
  • Cell Imaging/Staining
  • IF
  • RT-PCR
  • Flow Cytometry

All Interleukin Related Isoforms

More
Keywords
100 mg

Get Quote In-stock

Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Sign In
Register
Sign in to MedChemExpress
Register New Account

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • 1/16

    Human IgG4 kappa

  • 1/16

    Flow cytometry analysis of Raji cells labelling IL-4Rα with Dupilumab at 100nM (Red). Goat anti human IgG Fc(Alexa Fluor488) was used as the secondary antibody at 1/400 dilution. Isotype control - human IgG (Blue). Unlabeled control - Unlabelled cells (Gray).

  • 1/16

    Dupilumab purchased from MedChemExpress. Usage Cited in: ACS Nano. 2025 Sep 16;19(36):32361-32373. [Abstract]

    Customer Validation
     Dupilumab (5 μg/mL, 48 h). Cytokine concentrations measured in culture supernatants following drug treatments.

  • 1/16

    Dupilumab purchased from MedChemExpress. Usage Cited in: ACS Nano. 2025 Sep 16;19(36):32361-32373. [Abstract]

    Customer Validation
     Representative images of spheroids subjected to microfluidic deformation analysis, comparing untreated control, antifibrotic drug NTD, and anti-interleukin drugs TCZ, STX, DUP (Dupilumab; 5 μg/L; 48 h), and TRA.

  • 1/16

    Dupilumab purchased from MedChemExpress. Usage Cited in: ACS Nano. 2025 Sep 16;19(36):32361-32373. [Abstract]

    Customer Validation
     Confocal fluorescence images showing the expression of collagen-1 and α-SMA in spheroids treated with NTD, TCZ, STX, DUP (Dupilumab, 5 μg/L, 48 h), and TRA.

  • 1/16

    Dupilumab purchased from MedChemExpress. Usage Cited in: Allergy. 2025 Oct 22. [Abstract]

    Customer Validation
     Comparison of mRNA levels for SCGB1A1, FOXJ1, and MUC5AC in untreated, IL-13, AS1517499, and Dupilumab (10 μM, 6 h)-treated HNECs using RT-qPCR.

  • 1/16

    Dupilumab purchased from MedChemExpress. Usage Cited in: Allergy. 2025 Oct 22. [Abstract]

    Customer Validation
     Dupilumab (10 μM, 6 h). Flow cytometry analysis of changes in SCGB1A1+βIV­tubulin and SCGB1A1+MUC5AC+ clusters across treatment groups.

  • Dupilumab Chemical Structure
    1/16
  • Dupilumab
  • Flow cytometry analysis of Raji cells labelling IL-4Rα with Dupilumab at 100nM (Red). Goat anti human IgG Fc(Alexa Fluor488) was used as the secondary antibody at 1/400 dilution. Isotype control - human IgG (Blue). Unlabeled control - Unlabelled cells (Gray).