870087-36-8
Chemical Structure
Apilimod mesylate
Synonym(s): STA 5326 mesylate; LAM-002A; AIT-101 mesylate
- CAS No.: 870087-36-8
- Formula:C25H34N6O8S2
- Molecular Weight:610.70
IUPAC Name: (E)-4-(6-(2-(3-methylbenzylidene)hydrazinyl)-2-(2-(pyridin-2-yl)ethoxy)pyrimidin-4-yl)morpholine dimethanesulfonate
InChIKey: GAJWNIKZLYZYSY-OKUPSQOASA-N
SMILES: CC1=CC=CC(/C=N/NC2=CC(N3CCOCC3)=NC(OCCC4=CC=CC=N4)=N2)=C1.CS(=O)(O)=O.CS(=O)(O)=O
Biological Activity: Apilimod (STA 5326) mesylate is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively[1]. Apilimod is a potent and highly selective PIKfyve inhibitor.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Apilimod mesylate | 99.58% | Apilimod (STA 5326) mesylate is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively. Apilimod is a potent and highly selective PIKfyve inhibitor. | ||||||||||||||||||||
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Keywords
