Apilimod hydrochloride
Apilimod (STA 5326) hydrochloride is a PIKFYVE kinase inhibitor that promotes NLRP3 inflammatory vesicle activation and IL-1β secretion. Apilimod hydrochloride has been shown to inhibit host cell proteases, which may prevent viral invasion but also block antiviral immune responses, potentially exacerbating immunosuppression in COVID-19.
For research use only. We do not sell to patients.
- CAS No.: 870087-37-9
- Formula: C23H28Cl2N6O2
- Molecular Weight:491.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 870087-37-9
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Molecular Weight 491.41
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Formula C23H28Cl2N6O2
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SMILES
CC1=CC=CC(/C=N/NC2=CC(N3CCOCC3)=NC(OCCC4=CC=CC=N4)=N2)=C1.Cl.Cl
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Synonyms
STA 5326 hydrochloride; LAM-002A free base hydrochloride; AIT-101 hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Apilimod hydrochloride Related Classifications
HY-14644B Related Classifications
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